GPR176-DT

Summary

GPR176-DT (GPR176 divergent transcript, HGNC:54389) is a long non-coding RNA gene on chromosome 15q15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54389
Approved symbol	GPR176-DT
Name	GPR176 divergent transcript
Location	15q15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246863
Ensembl biotype	lncRNA
Entrez	100505534
RNAcentral	URS00026A259B — lncRNA, 2776 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000499797, ENST00000558675, ENST00000795012, ENST00000795013, ENST00000795014, ENST00000795015, ENST00000795016, ENST00000795017

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499797 — 2 exons

Exon	Start	End
ENSE00001967822	39921042	39921658
ENSE00001979407	39922787	39924899

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 70.22.

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	70.22	gold quality
right testis	UBERON:0004534	67.14	gold quality
left testis	UBERON:0004533	66.17	gold quality
testis	UBERON:0000473	64.90	gold quality
endothelial cell	CL:0000115	62.65	gold quality
sperm	CL:0000019	59.99	gold quality
male germ cell	CL:0000015	59.38	gold quality
ventricular zone	UBERON:0003053	59.18	gold quality
ganglionic eminence	UBERON:0004023	58.92	silver quality
cortical plate	UBERON:0005343	58.85	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.13	gold quality
granulocyte	CL:0000094	55.10	gold quality
cerebellar vermis	UBERON:0004720	54.23	gold quality
monocyte	CL:0000576	53.56	silver quality
mononuclear cell	CL:0000842	53.51	silver quality
hindlimb stylopod muscle	UBERON:0004252	53.29	silver quality
embryo	UBERON:0000922	52.26	silver quality
stromal cell of endometrium	CL:0002255	51.86	silver quality
calcaneal tendon	UBERON:0003701	50.28	silver quality
prefrontal cortex	UBERON:0000451	50.02	gold quality
bone marrow cell	CL:0002092	49.58	gold quality
Brodmann (1909) area 46	UBERON:0006483	49.30	gold quality
cervix squamous epithelium	UBERON:0006922	49.20	gold quality
hair follicle	UBERON:0002073	49.18	gold quality
islet of Langerhans	UBERON:0000006	48.99	gold quality
muscle of leg	UBERON:0001383	48.97	silver quality
olfactory bulb	UBERON:0002264	48.92	gold quality
myocardium	UBERON:0002349	48.87	gold quality
type B pancreatic cell	CL:0000169	48.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.