GPR50-AS1

Summary

GPR50-AS1 (GPR50 antisense RNA 1, HGNC:40259) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40259
Approved symbol	GPR50-AS1
Name	GPR50 antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234696
Ensembl biotype	lncRNA
Entrez	100128688
RNAcentral	URS0000A76A9D — lncRNA, 1614 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000454196, ENST00000835194, ENST00000835195

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454196 — 3 exons

Exon	Start	End
ENSE00001630033	151175192	151176270
ENSE00001641047	151177377	151177836
ENSE00001701135	151176795	151176875

Expression profiles

Bgee: expression breadth broad, 15 present calls, max score 93.75.

Top tissues by expression

15 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	93.75	gold quality
liver	UBERON:0002107	90.18	silver quality
stomach	UBERON:0000945	89.12	gold quality
ovary	UBERON:0000992	79.50	gold quality
lung	UBERON:0002048	77.51	silver quality
kidney	UBERON:0002113	71.70	silver quality
brain	UBERON:0000955	56.73	gold quality
pituitary gland	UBERON:0000007	56.21	gold quality
adenohypophysis	UBERON:0002196	52.26	gold quality
body of uterus	UBERON:0009853	49.08	gold quality
adipose tissue	UBERON:0001013	46.44	silver quality
placenta	UBERON:0001987	46.32	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	44.68	gold quality
Brodmann (1909) area 9	UBERON:0013540	44.43	silver quality
esophagus mucosa	UBERON:0002469	40.77	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.