GRASLND

Summary

GRASLND (glycosaminoglycan regulatory associated long non-coding RNA, HGNC:30963) is a long non-coding RNA gene on chromosome 2p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30963
Approved symbol	GRASLND
Name	glycosaminoglycan regulatory associated long non-coding RNA
Location	2p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228203
Ensembl biotype	lncRNA
Entrez	386597
RNAcentral	URS000075C923 — lncRNA, 2348 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 39 lncRNA

ENST00000418970, ENST00000424351, ENST00000426122, ENST00000437589, ENST00000439208, ENST00000653376, ENST00000654416, ENST00000654458, ENST00000655156, ENST00000655735, ENST00000656329, ENST00000657786, ENST00000659594, ENST00000660102, ENST00000660837, ENST00000661352, ENST00000661763, ENST00000663387, ENST00000666155, ENST00000666343, ENST00000668067, ENST00000668217, ENST00000668478, ENST00000669858, ENST00000670983, ENST00000671313, ENST00000779906, ENST00000779907, ENST00000779908, ENST00000779909, ENST00000779910, ENST00000779911, ENST00000779912, ENST00000779913, ENST00000779914, ENST00000779915, ENST00000779916, ENST00000779917, ENST00000779918

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418970 — 5 exons

Exon	Start	End
ENSE00001696172	6914193	6914350
ENSE00001740197	6916850	6917224
ENSE00001759473	6915823	6915967
ENSE00003871776	6918402	6918680
ENSE00004150692	6912273	6913664

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 84.70.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0143 / max 6.7129, expressed in 5 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26747	0.0143	5

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	84.70	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.01	gold quality
cerebellar hemisphere	UBERON:0002245	82.55	gold quality
cerebellar cortex	UBERON:0002129	82.42	gold quality
spleen	UBERON:0002106	81.80	gold quality
right frontal lobe	UBERON:0002810	81.78	gold quality
cerebellum	UBERON:0002037	81.13	gold quality
nucleus accumbens	UBERON:0001882	80.79	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.29	gold quality
prefrontal cortex	UBERON:0000451	80.18	gold quality
putamen	UBERON:0001874	80.00	gold quality
right adrenal gland cortex	UBERON:0035827	79.52	gold quality
caudate nucleus	UBERON:0001873	79.51	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.82	gold quality
left adrenal gland	UBERON:0001234	78.45	gold quality
right adrenal gland	UBERON:0001233	78.30	gold quality
left adrenal gland cortex	UBERON:0035825	77.57	gold quality
adrenal cortex	UBERON:0001235	77.04	gold quality
adrenal gland	UBERON:0002369	76.80	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	76.77	gold quality
anterior cingulate cortex	UBERON:0009835	76.72	gold quality
pancreas	UBERON:0001264	76.38	gold quality
frontal cortex	UBERON:0001870	76.11	gold quality
neocortex	UBERON:0001950	75.66	gold quality
sural nerve	UBERON:0015488	73.94	gold quality
brain	UBERON:0000955	72.11	gold quality
adrenal tissue	UBERON:0018303	72.02	gold quality
forebrain	UBERON:0001890	71.82	gold quality
primary visual cortex	UBERON:0002436	71.78	gold quality
cerebral cortex	UBERON:0000956	71.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.16

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis. (PMID:34560189)
• The Role of Long Non-Coding RNF144A-AS1 in Cancer Progression. (PMID:39014185)
• GRASLND regulates melanoma cell progression by targeting the miR-218-5p/STAM2 axis. (PMID:39060946)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.