GREB1L-DT

Summary

GREB1L-DT (GREB1L divergent transcript, HGNC:55323) is a long non-coding RNA gene on chromosome 18q11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55323
Approved symbol	GREB1L-DT
Name	GREB1L divergent transcript
Location	18q11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000265984
Ensembl biotype	lncRNA
Entrez	101927496
RNAcentral	URS00026A27EE — lncRNA, 471 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000579247, ENST00000834040, ENST00000834041, ENST00000834042, ENST00000834043, ENST00000834044, ENST00000834045, ENST00000834046, ENST00000834047, ENST00000834048, ENST00000834049, ENST00000834050, ENST00000834051, ENST00000834052, ENST00000834053, ENST00000834054, ENST00000834055, ENST00000834056, ENST00000834057

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000579247 — 2 exons

Exon	Start	End
ENSE00004251219	21241277	21242116
ENSE00004251230	21240618	21241007

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 88.07.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.07	gold quality
cerebellar vermis	UBERON:0004720	72.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.26	gold quality
quadriceps femoris	UBERON:0001377	64.94	gold quality
spleen	UBERON:0002106	64.15	silver quality
thymus	UBERON:0002370	63.35	silver quality
hypothalamus	UBERON:0001898	63.23	gold quality
bone marrow	UBERON:0002371	62.88	silver quality
skeletal muscle tissue	UBERON:0001134	62.54	gold quality
nucleus accumbens	UBERON:0001882	61.37	gold quality
prefrontal cortex	UBERON:0000451	59.17	gold quality
myometrium	UBERON:0001296	58.68	gold quality
prostate gland	UBERON:0002367	58.11	gold quality
muscle of leg	UBERON:0001383	57.79	gold quality
amygdala	UBERON:0001876	57.36	gold quality
gastrocnemius	UBERON:0001388	57.28	gold quality
thoracic mammary gland	UBERON:0005200	56.66	gold quality
right ovary	UBERON:0002118	55.84	gold quality
ectocervix	UBERON:0012249	55.64	gold quality
liver	UBERON:0002107	55.38	gold quality
smooth muscle tissue	UBERON:0001135	55.32	gold quality
substantia nigra	UBERON:0002038	55.17	gold quality
omental fat pad	UBERON:0010414	54.68	gold quality
putamen	UBERON:0001874	54.67	gold quality
descending thoracic aorta	UBERON:0002345	54.60	gold quality
adipose tissue	UBERON:0001013	54.40	gold quality
left uterine tube	UBERON:0001303	54.39	gold quality
ovary	UBERON:0000992	54.24	gold quality
fallopian tube	UBERON:0003889	53.98	gold quality
subcutaneous adipose tissue	UBERON:0002190	53.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• GREB1L overexpression correlates with prognosis and immune cell infiltration in lung adenocarcinoma. (PMID:34168239)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.