GRHL3-AS1

Summary

GRHL3-AS1 (GRHL3 antisense RNA 1, HGNC:41119) is a long non-coding RNA gene on chromosome 1p36.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41119
Approved symbol	GRHL3-AS1
Name	GRHL3 antisense RNA 1
Location	1p36.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232298
Ensembl biotype	lncRNA
Entrez	105376871
RNAcentral	URS00026A1B82 — lncRNA, 5216 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000437965, ENST00000752249

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437965 — 5 exons

Exon	Start	End
ENSE00001636882	24307556	24307780
ENSE00001683146	24311879	24311992
ENSE00001702761	24310675	24310817
ENSE00001714419	24321666	24321901
ENSE00001806660	24308178	24308315

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 87.10.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.10	gold quality
corpus callosum	UBERON:0002336	59.33	gold quality
skeletal muscle tissue	UBERON:0001134	58.99	silver quality
esophagus mucosa	UBERON:0002469	58.39	gold quality
lower esophagus mucosa	UBERON:0035834	57.40	gold quality
urinary bladder	UBERON:0001255	56.29	gold quality
esophagus	UBERON:0001043	54.94	gold quality
vagina	UBERON:0000996	54.54	gold quality
monocyte	CL:0000576	54.07	gold quality
muscle of leg	UBERON:0001383	54.04	gold quality
gastrocnemius	UBERON:0001388	53.94	gold quality
right lobe of liver	UBERON:0001114	53.81	gold quality
blood	UBERON:0000178	53.52	silver quality
liver	UBERON:0002107	53.26	gold quality
gall bladder	UBERON:0002110	52.07	gold quality
islet of Langerhans	UBERON:0000006	51.36	gold quality
lymph node	UBERON:0000029	51.04	gold quality
uterine cervix	UBERON:0000002	50.77	gold quality
tonsil	UBERON:0002372	50.46	silver quality
prefrontal cortex	UBERON:0000451	50.43	silver quality
cortex of kidney	UBERON:0001225	50.07	gold quality
duodenum	UBERON:0002114	50.02	gold quality
right testis	UBERON:0004534	49.61	gold quality
ectocervix	UBERON:0012249	49.51	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.43	gold quality
testis	UBERON:0000473	48.97	gold quality
vermiform appendix	UBERON:0001154	48.76	gold quality
left testis	UBERON:0004533	48.64	gold quality
superior frontal gyrus	UBERON:0002661	48.32	gold quality
placenta	UBERON:0001987	48.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.