GRIK1-AS1

Summary

GRIK1-AS1 (GRIK1 antisense RNA 1, HGNC:16458) is a long non-coding RNA gene on chromosome 21q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16458
Approved symbol	GRIK1-AS1
Name	GRIK1 antisense RNA 1
Location	21q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000174680
Ensembl biotype	lncRNA
Entrez	642976
RNAcentral	URS000075B565 — lncRNA, 1103 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000309331, ENST00000412579, ENST00000413131, ENST00000423221, ENST00000455392, ENST00000658262, ENST00000658460

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000309331 — 3 exons

Exon	Start	End
ENSE00001191923	29758831	29759010
ENSE00001429814	29748938	29749145
ENSE00001681171	29763578	29764002

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 68.10.

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	68.10	gold quality
bone marrow cell	CL:0002092	67.86	silver quality
cortical plate	UBERON:0005343	67.47	gold quality
ventricular zone	UBERON:0003053	66.98	gold quality
amygdala	UBERON:0001876	66.68	gold quality
ganglionic eminence	UBERON:0004023	64.50	gold quality
stromal cell of endometrium	CL:0002255	63.85	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.81	gold quality
cerebellar vermis	UBERON:0004720	63.75	gold quality
caudate nucleus	UBERON:0001873	62.16	gold quality
buccal mucosa cell	CL:0002336	61.91	gold quality
anterior cingulate cortex	UBERON:0009835	61.87	gold quality
spinal cord	UBERON:0002240	61.83	gold quality
Brodmann (1909) area 9	UBERON:0013540	60.86	gold quality
hypothalamus	UBERON:0001898	60.72	gold quality
prefrontal cortex	UBERON:0000451	60.45	gold quality
putamen	UBERON:0001874	60.32	gold quality
body of pancreas	UBERON:0001150	60.26	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.04	gold quality
right coronary artery	UBERON:0001625	59.42	gold quality
gastrocnemius	UBERON:0001388	59.34	gold quality
muscle of leg	UBERON:0001383	59.20	gold quality
substantia nigra	UBERON:0002038	58.68	gold quality
cerebellar hemisphere	UBERON:0002245	58.66	gold quality
cerebellar cortex	UBERON:0002129	58.64	gold quality
right frontal lobe	UBERON:0002810	58.63	gold quality
monocyte	CL:0000576	58.49	gold quality
metanephros cortex	UBERON:0010533	58.35	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	57.90	gold quality
corpus callosum	UBERON:0002336	57.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.