GRK3-AS1

Summary

GRK3-AS1 (GRK3 antisense RNA 1, HGNC:55679) is a long non-coding RNA gene on chromosome 22q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55679
Approved symbol	GRK3-AS1
Name	GRK3 antisense RNA 1
Location	22q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234884
Ensembl biotype	lncRNA
Entrez	100996404
RNAcentral	URS00026A258E — lncRNA, 1208 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 37 — 37 lncRNA

ENST00000412773, ENST00000422876, ENST00000453811, ENST00000661676, ENST00000666865, ENST00000668059, ENST00000818403, ENST00000818404, ENST00000818405, ENST00000818406, ENST00000818407, ENST00000818408, ENST00000818409, ENST00000818410, ENST00000818411, ENST00000818412, ENST00000818413, ENST00000818414, ENST00000818415, ENST00000818416, ENST00000818417, ENST00000818418, ENST00000818419, ENST00000818420, ENST00000818421, ENST00000818422, ENST00000818423, ENST00000818424, ENST00000818425, ENST00000818426, ENST00000818427, ENST00000818428, ENST00000818429, ENST00000818430, ENST00000818431, ENST00000818432, ENST00000818433

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412773 — 2 exons

Exon	Start	End
ENSE00004222377	25561117	25561498
ENSE00004222387	25564357	25564748

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 86.81.

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	86.81	gold quality
right testis	UBERON:0004534	85.51	gold quality
sperm	CL:0000019	85.33	gold quality
testis	UBERON:0000473	83.40	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.79	silver quality
bone marrow cell	CL:0002092	69.30	silver quality
cortical plate	UBERON:0005343	67.29	gold quality
islet of Langerhans	UBERON:0000006	61.94	gold quality
monocyte	CL:0000576	59.40	gold quality
leukocyte	CL:0000738	59.31	gold quality
granulocyte	CL:0000094	57.62	gold quality
pancreas	UBERON:0001264	54.91	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
calcaneal tendon	UBERON:0003701	54.29	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
epithelial cell of pancreas	CL:0000083	53.30	gold quality
right uterine tube	UBERON:0001302	53.19	gold quality
prefrontal cortex	UBERON:0000451	52.98	gold quality
tibialis anterior	UBERON:0001385	52.80	silver quality
lymph node	UBERON:0000029	52.31	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.01	gold quality
ileal mucosa	UBERON:0000331	51.99	silver quality
subcutaneous adipose tissue	UBERON:0002190	51.92	gold quality
muscle of leg	UBERON:0001383	51.86	gold quality
gastrocnemius	UBERON:0001388	51.31	gold quality
vermiform appendix	UBERON:0001154	50.93	gold quality
left coronary artery	UBERON:0001626	50.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.