GRK5-AS1

Summary

GRK5-AS1 (GRK5 antisense RNA 1, HGNC:58234) is a long non-coding RNA gene on chromosome 10q26.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58234
Approved symbol	GRK5-AS1
Name	GRK5 antisense RNA 1
Location	10q26.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236426
Ensembl biotype	lncRNA
Entrez	105378511
RNAcentral	URS0002A3F775 — lncRNA, 798 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000457948, ENST00000625697, ENST00000630276, ENST00000802945

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457948 — 2 exons

Exon	Start	End
ENSE00004192909	119334457	119334992
ENSE00004192913	119335921	119336182

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 77.05.

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	77.05	gold quality
adrenal tissue	UBERON:0018303	73.43	gold quality
bone marrow cell	CL:0002092	70.24	silver quality
skeletal muscle tissue	UBERON:0001134	69.37	silver quality
sural nerve	UBERON:0015488	66.58	silver quality
calcaneal tendon	UBERON:0003701	65.04	gold quality
bone marrow	UBERON:0002371	65.03	gold quality
stromal cell of endometrium	CL:0002255	63.33	gold quality
blood	UBERON:0000178	60.77	gold quality
right atrium auricular region	UBERON:0006631	60.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.84	gold quality
left testis	UBERON:0004533	58.82	gold quality
liver	UBERON:0002107	58.57	gold quality
lung	UBERON:0002048	58.43	gold quality
testis	UBERON:0000473	58.40	gold quality
right testis	UBERON:0004534	58.38	gold quality
urinary bladder	UBERON:0001255	57.94	gold quality
lymph node	UBERON:0000029	56.93	gold quality
heart	UBERON:0000948	56.89	gold quality
tonsil	UBERON:0002372	56.69	gold quality
ovary	UBERON:0000992	56.24	gold quality
heart left ventricle	UBERON:0002084	55.74	gold quality
left ovary	UBERON:0002119	55.67	gold quality
adrenal gland	UBERON:0002369	55.34	gold quality
duodenum	UBERON:0002114	55.25	gold quality
upper lobe of left lung	UBERON:0008952	55.08	gold quality
monocyte	CL:0000576	54.83	gold quality
right ovary	UBERON:0002118	54.68	gold quality
ascending aorta	UBERON:0001496	54.59	gold quality
lower esophagus mucosa	UBERON:0035834	54.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.