GRM3-AS1

Summary

GRM3-AS1 (GRM3 antisense RNA 1, HGNC:40264) is a long non-coding RNA gene on chromosome 7q21.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40264
Approved symbol	GRM3-AS1
Name	GRM3 antisense RNA 1
Location	7q21.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233073
Ensembl biotype	lncRNA
Entrez	105375382
RNAcentral	URS0000EEF1DA — lncRNA, 3684 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000418031, ENST00000423979, ENST00000452471, ENST00000785213, ENST00000785214, ENST00000785215

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418031 — 4 exons

Exon	Start	End
ENSE00001624910	86786270	86787539
ENSE00001689714	86782357	86784657
ENSE00003865920	86802262	86802284
ENSE00003884988	86803320	86803409

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 68.84.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	68.84	gold quality
cerebellar vermis	UBERON:0004720	65.26	gold quality
bone marrow	UBERON:0002371	64.16	silver quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
cortical plate	UBERON:0005343	63.90	gold quality
ganglionic eminence	UBERON:0004023	60.20	gold quality
ventricular zone	UBERON:0003053	59.09	silver quality
thymus	UBERON:0002370	59.06	silver quality
right hemisphere of cerebellum	UBERON:0014890	57.85	gold quality
cerebellar cortex	UBERON:0002129	56.16	gold quality
cerebellum	UBERON:0002037	56.12	gold quality
cerebellar hemisphere	UBERON:0002245	55.99	gold quality
adrenal tissue	UBERON:0018303	55.07	gold quality
prefrontal cortex	UBERON:0000451	54.17	gold quality
primary visual cortex	UBERON:0002436	53.15	gold quality
duodenum	UBERON:0002114	52.81	gold quality
substantia nigra	UBERON:0002038	52.07	gold quality
endometrium	UBERON:0001295	51.80	silver quality
rectum	UBERON:0001052	51.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	50.83	silver quality
placenta	UBERON:0001987	50.69	gold quality
spinal cord	UBERON:0002240	50.41	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.38	gold quality
blood	UBERON:0000178	50.05	gold quality
frontal cortex	UBERON:0001870	49.91	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.64	gold quality
calcaneal tendon	UBERON:0003701	49.14	silver quality
monocyte	CL:0000576	49.11	silver quality
superior frontal gyrus	UBERON:0002661	49.09	gold quality
brain	UBERON:0000955	48.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.