GRM5-AS1

Summary

GRM5-AS1 (GRM5 antisense RNA 1, HGNC:40265) is a long non-coding RNA gene on chromosome 11q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40265
Approved symbol	GRM5-AS1
Name	GRM5 antisense RNA 1
Location	11q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255082
Ensembl biotype	lncRNA
Entrez	100873989
RNAcentral	URS000058215F — lncRNA, 4821 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000526448, ENST00000531994

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526448 — 6 exons

Exon	Start	End
ENSE00002149453	88512252	88512348
ENSE00002153982	88522891	88522967
ENSE00002158772	88512064	88512164
ENSE00002164096	88524002	88524054
ENSE00002181784	88504576	88508939
ENSE00002188097	88511751	88511879

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 96.11.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.11	gold quality
superior frontal gyrus	UBERON:0002661	87.52	gold quality
Brodmann (1909) area 9	UBERON:0013540	86.63	gold quality
cortical plate	UBERON:0005343	85.50	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.27	gold quality
prefrontal cortex	UBERON:0000451	83.68	gold quality
nucleus accumbens	UBERON:0001882	83.66	gold quality
anterior cingulate cortex	UBERON:0009835	83.51	gold quality
cerebral cortex	UBERON:0000956	83.33	gold quality
primary visual cortex	UBERON:0002436	83.12	gold quality
frontal cortex	UBERON:0001870	82.78	gold quality
caudate nucleus	UBERON:0001873	82.69	gold quality
right frontal lobe	UBERON:0002810	81.78	gold quality
Ammon’s horn	UBERON:0001954	81.59	gold quality
putamen	UBERON:0001874	80.98	gold quality
amygdala	UBERON:0001876	80.41	gold quality
hypothalamus	UBERON:0001898	77.13	gold quality
brain	UBERON:0000955	76.77	gold quality
corpus callosum	UBERON:0002336	73.67	gold quality
substantia nigra	UBERON:0002038	73.04	gold quality
ventricular zone	UBERON:0003053	70.40	gold quality
sural nerve	UBERON:0015488	68.99	gold quality
ganglionic eminence	UBERON:0004023	64.96	gold quality
placenta	UBERON:0001987	64.56	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	64.55	gold quality
multicellular organism	UBERON:0000468	64.26	gold quality
monocyte	CL:0000576	63.36	gold quality
descending thoracic aorta	UBERON:0002345	62.79	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.63	gold quality
cerebellar cortex	UBERON:0002129	60.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.