GRM7-AS3

Summary

GRM7-AS3 (GRM7 antisense RNA 3, HGNC:42444) is a long non-coding RNA gene on chromosome 3p26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42444
Approved symbol	GRM7-AS3
Name	GRM7 antisense RNA 3
Location	3p26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226258
Ensembl biotype	lncRNA
Entrez	101927347
RNAcentral	URS000075A0C6 — lncRNA, 497 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000412629, ENST00000417482, ENST00000424366, ENST00000445675, ENST00000449158, ENST00000452244, ENST00000454410, ENST00000455623, ENST00000458713, ENST00000670757, ENST00000812336, ENST00000812337, ENST00000812338, ENST00000812339, ENST00000812340, ENST00000812341, ENST00000812342, ENST00000812343, ENST00000812344, ENST00000812345, ENST00000812346, ENST00000812347, ENST00000812348, ENST00000812349, ENST00000812350, ENST00000812351, ENST00000812352, ENST00000812353, ENST00000812354, ENST00000812355

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412629 — 4 exons

Exon	Start	End
ENSE00001614379	6635087	6635197
ENSE00004211270	6805389	6805483
ENSE00004211272	6631555	6632579
ENSE00004211286	6791053	6791141

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 88.35.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0147 / max 13.5325, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
40911	0.0102	3
40912	0.0045	3

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.35	gold quality
left testis	UBERON:0004533	82.56	gold quality
testis	UBERON:0000473	82.28	gold quality
right testis	UBERON:0004534	80.88	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.14	gold quality
islet of Langerhans	UBERON:0000006	66.58	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
bone marrow	UBERON:0002371	61.91	gold quality
thymus	UBERON:0002370	60.69	silver quality
rectum	UBERON:0001052	60.61	gold quality
pancreas	UBERON:0001264	60.15	gold quality
monocyte	CL:0000576	59.17	gold quality
skeletal muscle tissue	UBERON:0001134	58.87	silver quality
urinary bladder	UBERON:0001255	58.69	silver quality
blood	UBERON:0000178	58.60	gold quality
primary visual cortex	UBERON:0002436	57.20	gold quality
sural nerve	UBERON:0015488	57.02	silver quality
endometrium	UBERON:0001295	56.67	gold quality
placenta	UBERON:0001987	56.30	gold quality
superior frontal gyrus	UBERON:0002661	56.16	gold quality
cortex of kidney	UBERON:0001225	56.14	gold quality
corpus callosum	UBERON:0002336	55.86	gold quality
multicellular organism	UBERON:0000468	55.36	gold quality
prefrontal cortex	UBERON:0000451	55.00	gold quality
lung	UBERON:0002048	54.60	gold quality
gastrocnemius	UBERON:0001388	54.05	gold quality
heart	UBERON:0000948	53.89	gold quality
kidney	UBERON:0002113	52.17	gold quality
prostate gland	UBERON:0002367	51.11	silver quality
liver	UBERON:0002107	50.70	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.