GRM8-AS1

Summary

GRM8-AS1 (GRM8 antisense RNA 1, HGNC:40268) is a long non-coding RNA gene on chromosome 7q31.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40268
Approved symbol	GRM8-AS1
Name	GRM8 antisense RNA 1
Location	7q31.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236340
Ensembl biotype	lncRNA
Entrez	101928333
RNAcentral	URS000075D3C7 — lncRNA, 1927 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000413812, ENST00000450061, ENST00000667616

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413812 — 3 exons

Exon	Start	End
ENSE00001621262	127228373	127229921
ENSE00001649893	127219467	127219702
ENSE00001746640	127215127	127215253

Expression profiles

Bgee: expression breadth broad, 22 present calls, max score 82.71.

Top tissues by expression

161 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	82.71	silver quality
left testis	UBERON:0004533	57.19	gold quality
monocyte	CL:0000576	56.98	gold quality
right testis	UBERON:0004534	56.33	gold quality
testis	UBERON:0000473	56.16	gold quality
vermiform appendix	UBERON:0001154	50.22	gold quality
gastrocnemius	UBERON:0001388	47.56	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	46.53	silver quality
corpus callosum	UBERON:0002336	44.55	silver quality
caecum	UBERON:0001153	43.42	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
anatomical system	UBERON:0000467	42.38	gold quality
material anatomical entity	UBERON:0000465	42.29	gold quality
blood	UBERON:0000178	42.24	gold quality
multicellular organism	UBERON:0000468	42.19	gold quality
buccal mucosa cell	CL:0002336	41.94	gold quality
skin of leg	UBERON:0001511	41.91	silver quality
anterior cingulate cortex	UBERON:0009835	41.43	silver quality
cortex of kidney	UBERON:0001225	41.42	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
putamen	UBERON:0001874	41.31	silver quality
tendon	UBERON:0000043	41.18	gold quality
tibial artery	UBERON:0007610	41.17	silver quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.