GRPEL2-AS1

Summary

GRPEL2-AS1 (GRPEL2 antisense RNA 1, HGNC:48999) is a long non-coding RNA gene on chromosome 5q32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48999
Approved symbol	GRPEL2-AS1
Name	GRPEL2 antisense RNA 1
Location	5q32
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-394O4.4
Ensembl gene	ENSG00000253618
Ensembl biotype	lncRNA
Entrez	106144529
RNAcentral	URS0000098CAD — lncRNA, 401 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000521295, ENST00000757705

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000521295 — 2 exons

Exon	Start	End
ENSE00004109081	149348110	149348398
ENSE00004109082	149357525	149357820

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 81.14.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lower esophagus mucosa	UBERON:0035834	81.14	gold quality
cortical plate	UBERON:0005343	73.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.31	gold quality
bone marrow cell	CL:0002092	67.43	silver quality
skeletal muscle tissue	UBERON:0001134	67.01	gold quality
esophagus mucosa	UBERON:0002469	66.57	gold quality
bone marrow	UBERON:0002371	65.72	gold quality
upper lobe of left lung	UBERON:0008952	65.61	gold quality
stromal cell of endometrium	CL:0002255	64.77	gold quality
duodenum	UBERON:0002114	64.52	gold quality
right lung	UBERON:0002167	64.45	gold quality
endometrium	UBERON:0001295	64.29	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.06	gold quality
vermiform appendix	UBERON:0001154	63.82	gold quality
lung	UBERON:0002048	63.64	gold quality
lymph node	UBERON:0000029	63.49	gold quality
adipose tissue	UBERON:0001013	63.29	gold quality
apex of heart	UBERON:0002098	62.81	gold quality
omental fat pad	UBERON:0010414	62.34	gold quality
placenta	UBERON:0001987	62.12	gold quality
cortex of kidney	UBERON:0001225	61.92	gold quality
islet of Langerhans	UBERON:0000006	61.83	gold quality
gall bladder	UBERON:0002110	61.56	gold quality
smooth muscle tissue	UBERON:0001135	61.04	gold quality
esophagus	UBERON:0001043	60.80	gold quality
thoracic mammary gland	UBERON:0005200	60.65	gold quality
metanephros cortex	UBERON:0010533	60.62	gold quality
muscle of leg	UBERON:0001383	60.27	gold quality
heart left ventricle	UBERON:0002084	60.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.