GSCAR

Summary

GSCAR (glioma stem cell associated long noncoding RNA, HGNC:56879) is a long non-coding RNA gene on chromosome 5q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56879
Approved symbol	GSCAR
Name	glioma stem cell associated long noncoding RNA
Location	5q14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250377
Ensembl biotype	lncRNA
Entrez	124901024
RNAcentral	URS0002A496D5 — lncRNA, 2844 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000508719, ENST00000653354, ENST00000659756, ENST00000663453, ENST00000666338, ENST00000788290, ENST00000788291, ENST00000788292, ENST00000788293, ENST00000788294, ENST00000788295, ENST00000788296, ENST00000788297, ENST00000788298, ENST00000788299, ENST00000788300, ENST00000788301, ENST00000788302, ENST00000788303, ENST00000788304, ENST00000788305, ENST00000788306

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508719 — 3 exons

Exon	Start	End
ENSE00004166730	88691761	88692085
ENSE00004166735	88693547	88694033
ENSE00004166754	88692326	88692894

Expression profiles

Bgee: expression breadth broad, 62 present calls, max score 87.28.

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	87.28	gold quality
ventricular zone	UBERON:0003053	84.17	gold quality
ganglionic eminence	UBERON:0004023	80.81	gold quality
prefrontal cortex	UBERON:0000451	68.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.07	gold quality
cerebellar hemisphere	UBERON:0002245	65.83	gold quality
right frontal lobe	UBERON:0002810	65.82	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.78	gold quality
cerebellar cortex	UBERON:0002129	65.73	gold quality
primary visual cortex	UBERON:0002436	64.72	gold quality
anterior cingulate cortex	UBERON:0009835	64.66	gold quality
neocortex	UBERON:0001950	64.19	gold quality
cerebellum	UBERON:0002037	64.05	gold quality
frontal cortex	UBERON:0001870	63.10	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.84	gold quality
cerebral cortex	UBERON:0000956	61.33	gold quality
middle temporal gyrus	UBERON:0002771	60.30	gold quality
pancreatic ductal cell	CL:0002079	60.15	silver quality
hindlimb stylopod muscle	UBERON:0004252	59.75	gold quality
occipital lobe	UBERON:0002021	58.50	gold quality
muscle of leg	UBERON:0001383	57.52	gold quality
gastrocnemius	UBERON:0001388	57.31	gold quality
brain	UBERON:0000955	55.97	gold quality
Ammon’s horn	UBERON:0001954	55.65	gold quality
granulocyte	CL:0000094	55.36	gold quality
forebrain	UBERON:0001890	55.27	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
epithelial cell of pancreas	CL:0000083	54.67	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.