GSK3B-DT

Summary

GSK3B-DT (GSK3B divergent transcript, HGNC:55635) is a long non-coding RNA gene on chromosome 3q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55635
Approved symbol	GSK3B-DT
Name	GSK3B divergent transcript
Location	3q13.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	GPNCA
Ensembl gene	ENSG00000242622
Ensembl biotype	lncRNA
Entrez	107986119
RNAcentral	URS00026A22FE — lncRNA, 2881 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000469070, ENST00000484076, ENST00000485898, ENST00000686307, ENST00000834988, ENST00000834989, ENST00000834990, ENST00000834991, ENST00000834992, ENST00000834993, ENST00000834994, ENST00000834995, ENST00000834996, ENST00000834997, ENST00000834998, ENST00000834999, ENST00000835000, ENST00000835001, ENST00000835002, ENST00000835003

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000469070 — 2 exons

Exon	Start	End
ENSE00004252997	120098714	120099385
ENSE00004253003	120094737	120095778

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 80.31.

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.31	gold quality
buccal mucosa cell	CL:0002336	79.39	silver quality
pancreatic ductal cell	CL:0002079	77.46	silver quality
right testis	UBERON:0004534	75.80	gold quality
left testis	UBERON:0004533	75.74	gold quality
right uterine tube	UBERON:0001302	75.47	gold quality
testis	UBERON:0000473	74.33	gold quality
bone marrow cell	CL:0002092	72.92	gold quality
adenohypophysis	UBERON:0002196	72.85	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.79	gold quality
pituitary gland	UBERON:0000007	72.55	gold quality
sural nerve	UBERON:0015488	72.45	gold quality
metanephros cortex	UBERON:0010533	72.41	gold quality
mucosa of transverse colon	UBERON:0004991	72.14	gold quality
apex of heart	UBERON:0002098	71.56	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.37	gold quality
ganglionic eminence	UBERON:0004023	71.31	gold quality
right ovary	UBERON:0002118	71.28	gold quality
stromal cell of endometrium	CL:0002255	71.26	gold quality
minor salivary gland	UBERON:0001830	71.07	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.07	gold quality
cerebellar hemisphere	UBERON:0002245	71.00	gold quality
cerebellar cortex	UBERON:0002129	70.94	gold quality
right lobe of thyroid gland	UBERON:0001119	70.84	gold quality
body of uterus	UBERON:0009853	70.79	gold quality
left ovary	UBERON:0002119	70.37	gold quality
calcaneal tendon	UBERON:0003701	69.94	gold quality
cortical plate	UBERON:0005343	69.83	gold quality
adrenal tissue	UBERON:0018303	69.68	gold quality
cerebellum	UBERON:0002037	69.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.