GSN-AS1
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Also known as MOST2
Summary
GSN-AS1 (GSN antisense RNA 1, HGNC:23372) is a long non-coding RNA gene on chromosome 9q33.2.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:23372 |
| Approved symbol | GSN-AS1 |
| Name | GSN antisense RNA 1 |
| Location | 9q33.2 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | MOST2 |
| Ensembl gene | ENSG00000235865 |
| Ensembl biotype | lncRNA |
| Entrez | 57000 |
| RNAcentral | URS000075B06F — lncRNA, 4770 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000414544
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000414544 — 1 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001611681 | 121280768 | 121285530 |
Expression profiles
Bgee: expression breadth ubiquitous, 148 present calls, max score 82.35.
Top tissues by expression
238 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 82.35 | gold quality |
| sural nerve | UBERON:0015488 | 81.99 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 74.83 | gold quality |
| colonic epithelium | UBERON:0000397 | 74.19 | gold quality |
| bone marrow cell | CL:0002092 | 70.78 | silver quality |
| stromal cell of endometrium | CL:0002255 | 70.05 | gold quality |
| calcaneal tendon | UBERON:0003701 | 66.48 | gold quality |
| corpus callosum | UBERON:0002336 | 64.04 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 63.40 | gold quality |
| spinal cord | UBERON:0002240 | 61.30 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 61.25 | gold quality |
| tibial nerve | UBERON:0001323 | 60.86 | gold quality |
| thoracic aorta | UBERON:0001515 | 59.67 | gold quality |
| ascending aorta | UBERON:0001496 | 59.32 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 58.41 | gold quality |
| lower esophagus | UBERON:0013473 | 58.35 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 58.09 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 57.39 | gold quality |
| prefrontal cortex | UBERON:0000451 | 57.24 | gold quality |
| aorta | UBERON:0000947 | 57.14 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 57.06 | gold quality |
| tendon | UBERON:0000043 | 57.02 | gold quality |
| right coronary artery | UBERON:0001625 | 56.90 | gold quality |
| tonsil | UBERON:0002372 | 56.54 | silver quality |
| gingival epithelium | UBERON:0001949 | 56.15 | gold quality |
| left coronary artery | UBERON:0001626 | 56.01 | gold quality |
| popliteal artery | UBERON:0002250 | 55.40 | gold quality |
| tibial artery | UBERON:0007610 | 55.30 | gold quality |
| coronary artery | UBERON:0001621 | 55.21 | gold quality |
| body of uterus | UBERON:0009853 | 55.21 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 3.57 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): Finnish type amyloidosis