GTF2I-AS1

Summary

GTF2I-AS1 (GTF2I antisense RNA 1, HGNC:55572) is a long non-coding RNA gene on chromosome 7q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55572
Approved symbol	GTF2I-AS1
Name	GTF2I antisense RNA 1
Location	7q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232729
Ensembl biotype	lncRNA
Entrez	101926943
RNAcentral	URS000075CD50 — lncRNA, 841 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 31 lncRNA, 1 retained_intron

ENST00000434256, ENST00000450426, ENST00000594967, ENST00000595409, ENST00000601921, ENST00000619652, ENST00000669011, ENST00000789967, ENST00000789968, ENST00000789969, ENST00000789970, ENST00000789971, ENST00000789972, ENST00000789973, ENST00000789974, ENST00000789975, ENST00000789976, ENST00000789977, ENST00000789978, ENST00000789979, ENST00000789980, ENST00000789981, ENST00000789982, ENST00000789983, ENST00000789984, ENST00000789985, ENST00000789986, ENST00000789987, ENST00000789988, ENST00000789989, ENST00000789990, ENST00000789991

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434256 — 3 exons

Exon	Start	End
ENSE00001672106	74727402	74727522
ENSE00004169775	74699083	74700380
ENSE00004169802	74728705	74728967

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 83.75.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	83.75	gold quality
placenta	UBERON:0001987	81.70	gold quality
colonic epithelium	UBERON:0000397	80.46	gold quality
adrenal tissue	UBERON:0018303	80.27	gold quality
bone marrow cell	CL:0002092	79.28	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.54	gold quality
sural nerve	UBERON:0015488	76.86	gold quality
bone marrow	UBERON:0002371	73.46	gold quality
calcaneal tendon	UBERON:0003701	72.70	gold quality
right testis	UBERON:0004534	71.72	gold quality
superior frontal gyrus	UBERON:0002661	71.60	gold quality
testis	UBERON:0000473	71.44	gold quality
left testis	UBERON:0004533	71.43	gold quality
stromal cell of endometrium	CL:0002255	71.21	gold quality
primary visual cortex	UBERON:0002436	71.02	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.96	gold quality
tonsil	UBERON:0002372	70.72	gold quality
skeletal muscle tissue	UBERON:0001134	70.64	gold quality
cortical plate	UBERON:0005343	68.18	gold quality
endometrium	UBERON:0001295	68.15	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.02	gold quality
muscle tissue	UBERON:0002385	67.94	gold quality
cerebellar cortex	UBERON:0002129	66.86	gold quality
cerebellum	UBERON:0002037	66.85	gold quality
cerebellar hemisphere	UBERON:0002245	66.61	gold quality
right adrenal gland cortex	UBERON:0035827	66.21	gold quality
adrenal gland	UBERON:0002369	65.58	gold quality
ganglionic eminence	UBERON:0004023	65.42	gold quality
uterine cervix	UBERON:0000002	65.35	gold quality
liver	UBERON:0002107	65.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.51

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.