GTF3C2-AS1

Summary

GTF3C2-AS1 (GTF3C2 antisense RNA 1, HGNC:40269) is a long non-coding RNA gene on chromosome 2p23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40269
Approved symbol	GTF3C2-AS1
Name	GTF3C2 antisense RNA 1
Location	2p23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234945
Ensembl biotype	lncRNA
Entrez	100505624
RNAcentral	URS000075AFB3 — lncRNA, 841 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000416453, ENST00000585326, ENST00000585645, ENST00000587586, ENST00000588707, ENST00000589232, ENST00000589853, ENST00000590383, ENST00000590754, ENST00000592265, ENST00000608473, ENST00000625728, ENST00000626256, ENST00000655380, ENST00000662609, ENST00000732733, ENST00000732734

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416453 — 4 exons

Exon	Start	End
ENSE00001697877	27336292	27336470
ENSE00001770111	27337211	27337326
ENSE00004063371	27335525	27335720
ENSE00004063372	27337437	27337825

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 94.57.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0268 / max 32.9292, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19356	0.0165	3
19355	0.0103	3

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	94.57	gold quality
right testis	UBERON:0004534	89.37	gold quality
left testis	UBERON:0004533	88.58	gold quality
testis	UBERON:0000473	85.45	gold quality
sural nerve	UBERON:0015488	85.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.29	gold quality
bone marrow cell	CL:0002092	80.97	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.02	gold quality
tendon of biceps brachii	UBERON:0008188	76.76	gold quality
colonic epithelium	UBERON:0000397	76.44	gold quality
monocyte	CL:0000576	71.28	gold quality
leukocyte	CL:0000738	70.90	gold quality
adrenal tissue	UBERON:0018303	70.39	gold quality
tendon	UBERON:0000043	69.65	gold quality
ectocervix	UBERON:0012249	68.77	gold quality
minor salivary gland	UBERON:0001830	68.65	gold quality
right lobe of thyroid gland	UBERON:0001119	68.59	gold quality
calcaneal tendon	UBERON:0003701	68.37	gold quality
skin of abdomen	UBERON:0001416	68.34	gold quality
left lobe of thyroid gland	UBERON:0001120	67.88	gold quality
uterine cervix	UBERON:0000002	67.66	gold quality
left ovary	UBERON:0002119	67.54	gold quality
ganglionic eminence	UBERON:0004023	67.53	gold quality
cortical plate	UBERON:0005343	67.42	gold quality
skin of leg	UBERON:0001511	67.31	gold quality
thyroid gland	UBERON:0002046	67.08	gold quality
esophagus mucosa	UBERON:0002469	66.97	gold quality
body of uterus	UBERON:0009853	66.94	gold quality
body of pancreas	UBERON:0001150	66.87	gold quality
tibial nerve	UBERON:0001323	66.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.