GTSCR1

Summary

GTSCR1 (Gilles de la Tourette syndrome chromosome region, candidate 1, HGNC:18406) is a long non-coding RNA gene on chromosome 18q22.2.

Predicted to be located in membrane.

Source: NCBI Gene 220158 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18406
Approved symbol	GTSCR1
Name	Gilles de la Tourette syndrome chromosome region, candidate 1
Location	18q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263417
Ensembl biotype	lncRNA
Entrez	220158
RNAcentral	URS0000E60ADB — lncRNA, 695 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000582578, ENST00000745231, ENST00000745232, ENST00000745233, ENST00000745234, ENST00000745235

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000582578 — 3 exons

Exon	Start	End
ENSE00002719163	70642545	70642723
ENSE00004084982	70650610	70650959
ENSE00004084986	70630507	70630689

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 81.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1941 / max 58.2927, expressed in 40 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
172369	0.1169	33
172368	0.0772	26

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.49	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.40	gold quality
lymph node	UBERON:0000029	68.93	gold quality
tonsil	UBERON:0002372	63.39	gold quality
sural nerve	UBERON:0015488	62.85	gold quality
granulocyte	CL:0000094	62.69	gold quality
blood	UBERON:0000178	61.11	gold quality
leukocyte	CL:0000738	59.60	gold quality
gall bladder	UBERON:0002110	58.31	gold quality
vermiform appendix	UBERON:0001154	58.11	gold quality
bone marrow	UBERON:0002371	56.64	gold quality
liver	UBERON:0002107	54.75	gold quality
islet of Langerhans	UBERON:0000006	53.53	gold quality
adrenal gland	UBERON:0002369	53.08	gold quality
right lobe of liver	UBERON:0001114	52.57	gold quality
corpus callosum	UBERON:0002336	52.22	gold quality
kidney	UBERON:0002113	51.92	silver quality
cortex of kidney	UBERON:0001225	51.34	gold quality
multicellular organism	UBERON:0000468	51.19	gold quality
prefrontal cortex	UBERON:0000451	50.49	gold quality
body of pancreas	UBERON:0001150	49.42	gold quality
small intestine Peyer’s patch	UBERON:0003454	49.24	gold quality
monocyte	CL:0000576	48.91	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	48.49	gold quality
intestine	UBERON:0000160	47.31	gold quality
spleen	UBERON:0002106	46.94	gold quality
tibial nerve	UBERON:0001323	46.82	silver quality
adult mammalian kidney	UBERON:0000082	46.40	silver quality
heart	UBERON:0000948	46.31	gold quality
gastrocnemius	UBERON:0001388	46.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.20

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.