GUCY2C-AS1

Summary

GUCY2C-AS1 (GUCY2C antisense RNA 1, HGNC:56054) is a long non-coding RNA gene on chromosome 12p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56054
Approved symbol	GUCY2C-AS1
Name	GUCY2C antisense RNA 1
Location	12p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000214772
Ensembl biotype	lncRNA
Entrez	123706531
RNAcentral	URS00026A1C53 — lncRNA, 3248 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000501178, ENST00000786473, ENST00000786474, ENST00000786475, ENST00000786476, ENST00000786477, ENST00000786478, ENST00000786479

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501178 — 5 exons

Exon	Start	End
ENSE00002244693	14757595	14757963
ENSE00002247629	14665859	14666013
ENSE00002248457	14672266	14672314
ENSE00002311106	14718035	14718075
ENSE00002323092	14665655	14665697

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 84.36.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.36	gold quality
sural nerve	UBERON:0015488	78.45	silver quality
bone marrow cell	CL:0002092	69.10	silver quality
calcaneal tendon	UBERON:0003701	59.42	gold quality
blood	UBERON:0000178	58.96	gold quality
skeletal muscle tissue	UBERON:0001134	58.52	gold quality
monocyte	CL:0000576	56.79	gold quality
lymph node	UBERON:0000029	55.79	gold quality
bone marrow	UBERON:0002371	55.75	gold quality
placenta	UBERON:0001987	55.36	gold quality
esophagus mucosa	UBERON:0002469	55.31	gold quality
cortex of kidney	UBERON:0001225	55.13	gold quality
body of pancreas	UBERON:0001150	54.39	gold quality
pancreas	UBERON:0001264	54.35	gold quality
islet of Langerhans	UBERON:0000006	53.96	gold quality
liver	UBERON:0002107	53.26	gold quality
heart left ventricle	UBERON:0002084	53.02	gold quality
metanephros cortex	UBERON:0010533	53.02	gold quality
gall bladder	UBERON:0002110	52.72	gold quality
right lobe of liver	UBERON:0001114	51.68	gold quality
esophagus	UBERON:0001043	51.56	gold quality
descending thoracic aorta	UBERON:0002345	51.22	gold quality
heart	UBERON:0000948	51.20	gold quality
primary visual cortex	UBERON:0002436	51.05	gold quality
muscle of leg	UBERON:0001383	50.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.58	gold quality
kidney	UBERON:0002113	50.57	gold quality
vermiform appendix	UBERON:0001154	49.96	gold quality
tonsil	UBERON:0002372	49.95	gold quality
smooth muscle tissue	UBERON:0001135	49.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.54

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.