GZMH-AS1

Summary

GZMH-AS1 (GZMH and GMZB antisense RNA 1, HGNC:58166) is a long non-coding RNA gene.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58166
Approved symbol	GZMH-AS1
Name	GZMH and GMZB antisense RNA 1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL136018.1
Ensembl gene	ENSG00000258657
Ensembl biotype	lncRNA
Entrez	105370413
RNAcentral	URS0002A369A6 — lncRNA, 923 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000555300, ENST00000557736, ENST00000770595, ENST00000770596, ENST00000770597, ENST00000770598

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000555300 — 4 exons

Exon	Start	End
ENSE00002435740	24654647	24654707
ENSE00002437730	24595985	24596002
ENSE00002480709	24657525	24657774
ENSE00002536517	24622968	24623126

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 81.91.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.07	gold quality
sural nerve	UBERON:0015488	69.01	silver quality
cortical plate	UBERON:0005343	67.78	gold quality
tonsil	UBERON:0002372	67.77	gold quality
ventricular zone	UBERON:0003053	67.11	gold quality
bone marrow cell	CL:0002092	64.99	silver quality
hindlimb stylopod muscle	UBERON:0004252	62.63	gold quality
granulocyte	CL:0000094	62.46	gold quality
putamen	UBERON:0001874	60.97	gold quality
primary visual cortex	UBERON:0002436	59.90	gold quality
caudate nucleus	UBERON:0001873	59.67	gold quality
superior frontal gyrus	UBERON:0002661	59.51	gold quality
prefrontal cortex	UBERON:0000451	58.62	gold quality
islet of Langerhans	UBERON:0000006	58.37	gold quality
bone marrow	UBERON:0002371	58.23	gold quality
adrenal tissue	UBERON:0018303	58.12	gold quality
lymph node	UBERON:0000029	57.91	gold quality
adenohypophysis	UBERON:0002196	57.51	gold quality
nucleus accumbens	UBERON:0001882	57.13	gold quality
monocyte	CL:0000576	55.68	gold quality
pituitary gland	UBERON:0000007	55.44	gold quality
liver	UBERON:0002107	54.41	gold quality
endometrium	UBERON:0001295	54.34	gold quality
blood	UBERON:0000178	54.06	gold quality
gall bladder	UBERON:0002110	54.04	gold quality
frontal cortex	UBERON:0001870	53.61	gold quality
brain	UBERON:0000955	53.52	gold quality
placenta	UBERON:0001987	53.46	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.