GZMK-AS1

Summary

GZMK-AS1 (GZMK antisense RNA 1, HGNC:59043) is a long non-coding RNA gene on chromosome 5q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59043
Approved symbol	GZMK-AS1
Name	GZMK antisense RNA 1
Location	5q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000240535
Ensembl biotype	lncRNA
Entrez	102467081

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 12 lncRNA, 3 retained_intron

ENST00000371487, ENST00000595218, ENST00000596137, ENST00000596909, ENST00000607910, ENST00000608466, ENST00000608929, ENST00000608975, ENST00000609699, ENST00000609792, ENST00000611148, ENST00000615560, ENST00000615566, ENST00000616403, ENST00000618221

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000371487 — 3 exons

Exon	Start	End
ENSE00002020517	55022628	55022712
ENSE00002048237	55021299	55021522
ENSE00003711931	55023929	55024542

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 83.15.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.15	gold quality
granulocyte	CL:0000094	75.23	gold quality
lymph node	UBERON:0000029	71.67	gold quality
blood	UBERON:0000178	70.37	gold quality
bone marrow cell	CL:0002092	68.53	silver quality
bone marrow	UBERON:0002371	68.36	gold quality
calcaneal tendon	UBERON:0003701	67.56	gold quality
right coronary artery	UBERON:0001625	67.19	gold quality
vermiform appendix	UBERON:0001154	66.66	gold quality
tibial artery	UBERON:0007610	66.08	gold quality
popliteal artery	UBERON:0002250	65.98	gold quality
spleen	UBERON:0002106	65.85	gold quality
tonsil	UBERON:0002372	65.55	gold quality
myometrium	UBERON:0001296	65.44	gold quality
mucosa of transverse colon	UBERON:0004991	65.14	gold quality
body of uterus	UBERON:0009853	65.13	gold quality
ascending aorta	UBERON:0001496	65.12	gold quality
urinary bladder	UBERON:0001255	64.76	gold quality
duodenum	UBERON:0002114	64.57	gold quality
left testis	UBERON:0004533	64.45	gold quality
skeletal muscle tissue	UBERON:0001134	64.26	gold quality
testis	UBERON:0000473	64.24	gold quality
thoracic aorta	UBERON:0001515	64.10	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.07	gold quality
leukocyte	CL:0000738	62.75	gold quality
lower esophagus muscularis layer	UBERON:0035833	62.54	gold quality
lower esophagus	UBERON:0013473	62.50	gold quality
right testis	UBERON:0004534	62.25	gold quality
muscle layer of sigmoid colon	UBERON:0035805	62.23	gold quality
monocyte	CL:0000576	61.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.