H2AZ1-DT

Summary

H2AZ1-DT (H2AZ1 divergent transcript, HGNC:40271) is a long non-coding RNA gene on chromosome 4q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40271
Approved symbol	H2AZ1-DT
Name	H2AZ1 divergent transcript
Location	4q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245322
Ensembl biotype	lncRNA
Entrez	256880
RNAcentral	URS00007E3AF9 — lncRNA, 498 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000501976, ENST00000507494, ENST00000514624, ENST00000515026, ENST00000666876, ENST00000702428, ENST00000735770, ENST00000735771, ENST00000735772, ENST00000735773, ENST00000735774, ENST00000735775, ENST00000735776, ENST00000735777, ENST00000735778, ENST00000735779, ENST00000735780, ENST00000735781, ENST00000735782, ENST00000735783, ENST00000735784, ENST00000735785, ENST00000735786, ENST00000735787, ENST00000735788

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501976 — 4 exons

Exon	Start	End
ENSE00002071406	100025282	100025327
ENSE00002085723	100033934	100034020
ENSE00004068645	100037528	100039218
ENSE00004068648	99950456	99950680

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 78.93.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8956 / max 112.9415, expressed in 405 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
49026	0.8956	405

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	78.93	gold quality
sural nerve	UBERON:0015488	76.40	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.21	silver quality
colonic epithelium	UBERON:0000397	72.22	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.97	gold quality
bone marrow	UBERON:0002371	68.14	gold quality
right testis	UBERON:0004534	67.56	gold quality
ventricular zone	UBERON:0003053	67.29	gold quality
testis	UBERON:0000473	67.15	gold quality
left testis	UBERON:0004533	66.94	gold quality
skeletal muscle tissue	UBERON:0001134	66.41	gold quality
ganglionic eminence	UBERON:0004023	65.61	gold quality
tonsil	UBERON:0002372	65.20	gold quality
stromal cell of endometrium	CL:0002255	63.97	gold quality
cortical plate	UBERON:0005343	62.93	gold quality
prefrontal cortex	UBERON:0000451	62.79	gold quality
frontal cortex	UBERON:0001870	61.25	gold quality
right uterine tube	UBERON:0001302	60.94	gold quality
cerebral cortex	UBERON:0000956	60.39	gold quality
muscle tissue	UBERON:0002385	60.34	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.90	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	59.79	gold quality
Ammon’s horn	UBERON:0001954	59.78	gold quality
cerebellum	UBERON:0002037	59.74	gold quality
cerebellar hemisphere	UBERON:0002245	59.67	gold quality
anterior cingulate cortex	UBERON:0009835	59.66	gold quality
superior frontal gyrus	UBERON:0002661	59.64	gold quality
cerebellar cortex	UBERON:0002129	59.63	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.59	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.