HAFML

Summary

HAFML (HuR (ELAVL1) associated fibroblast migratory lncRNA, HGNC:56694) is a long non-coding RNA gene on chromosome 4q34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56694
Approved symbol	HAFML
Name	HuR (ELAVL1) associated fibroblast migratory lncRNA
Location	4q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248388
Ensembl biotype	lncRNA
Entrez	105377555
RNAcentral	URS00026A26E2 — lncRNA, 423 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000504017, ENST00000509194, ENST00000843108, ENST00000843109, ENST00000843110

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504017 — 4 exons

Exon	Start	End
ENSE00002023438	176679700	176679750
ENSE00002026773	176669621	176669709
ENSE00004268859	176705903	176706143
ENSE00004268864	176654174	176654276

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 94.09.

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.09	gold quality
right testis	UBERON:0004534	78.10	gold quality
left testis	UBERON:0004533	77.08	gold quality
testis	UBERON:0000473	77.00	gold quality
colonic epithelium	UBERON:0000397	72.27	gold quality
adrenal tissue	UBERON:0018303	67.40	gold quality
gall bladder	UBERON:0002110	64.26	gold quality
lymph node	UBERON:0000029	63.50	gold quality
islet of Langerhans	UBERON:0000006	60.03	gold quality
skeletal muscle tissue	UBERON:0001134	59.87	silver quality
lower esophagus mucosa	UBERON:0035834	59.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.85	gold quality
blood	UBERON:0000178	58.53	gold quality
calcaneal tendon	UBERON:0003701	58.07	gold quality
liver	UBERON:0002107	57.24	gold quality
muscle of leg	UBERON:0001383	57.09	gold quality
right lobe of thyroid gland	UBERON:0001119	57.05	gold quality
placenta	UBERON:0001987	56.88	gold quality
uterine cervix	UBERON:0000002	56.74	gold quality
endometrium	UBERON:0001295	56.47	gold quality
gastrocnemius	UBERON:0001388	56.44	gold quality
corpus callosum	UBERON:0002336	56.22	gold quality
prefrontal cortex	UBERON:0000451	56.07	gold quality
omental fat pad	UBERON:0010414	56.03	gold quality
thyroid gland	UBERON:0002046	55.61	gold quality
kidney	UBERON:0002113	55.41	gold quality
right lobe of liver	UBERON:0001114	55.37	gold quality
left lobe of thyroid gland	UBERON:0001120	55.29	gold quality
lung	UBERON:0002048	54.88	gold quality
heart left ventricle	UBERON:0002084	54.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.