HCFC1-AS1

Summary

HCFC1-AS1 (HCFC1 antisense RNA 1, HGNC:40273) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40273
Approved symbol	HCFC1-AS1
Name	HCFC1 antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235802
Ensembl biotype	lncRNA
Entrez	100873990
RNAcentral	URS000075CBA0 — lncRNA, 786 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000438219, ENST00000755970

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438219 — 3 exons

Exon	Start	End
ENSE00004105553	153969199	153969371
ENSE00004105554	153968886	153969070
ENSE00004105556	153969785	153970087

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 72.54.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	72.54	gold quality
bone marrow cell	CL:0002092	72.42	silver quality
monocyte	CL:0000576	71.91	gold quality
leukocyte	CL:0000738	71.34	gold quality
skeletal muscle tissue	UBERON:0001134	68.57	gold quality
sural nerve	UBERON:0015488	66.95	gold quality
pituitary gland	UBERON:0000007	66.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.77	gold quality
granulocyte	CL:0000094	64.64	gold quality
muscle of leg	UBERON:0001383	64.57	gold quality
adenohypophysis	UBERON:0002196	64.54	gold quality
blood	UBERON:0000178	63.34	gold quality
gastrocnemius	UBERON:0001388	62.99	gold quality
vermiform appendix	UBERON:0001154	62.33	gold quality
gall bladder	UBERON:0002110	62.30	gold quality
prefrontal cortex	UBERON:0000451	62.27	gold quality
tonsil	UBERON:0002372	61.21	gold quality
lymph node	UBERON:0000029	60.06	gold quality
smooth muscle tissue	UBERON:0001135	60.02	gold quality
cortex of kidney	UBERON:0001225	59.43	gold quality
putamen	UBERON:0001874	59.09	gold quality
frontal cortex	UBERON:0001870	58.82	gold quality
islet of Langerhans	UBERON:0000006	58.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.35	gold quality
placenta	UBERON:0001987	57.46	gold quality
anterior cingulate cortex	UBERON:0009835	57.46	gold quality
cerebral cortex	UBERON:0000956	57.25	gold quality
urinary bladder	UBERON:0001255	57.21	gold quality
superior frontal gyrus	UBERON:0002661	57.00	gold quality
brain	UBERON:0000955	56.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.