HCG21

Summary

HCG21 (HLA complex group 21, HGNC:31335) is a long non-coding RNA gene on chromosome 6p21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31335
Approved symbol	HCG21
Name	HLA complex group 21
Location	6p21
Locus type	RNA, long non-coding
Status	Approved
Aliases	AB023048.2, NCRNA00150
Ensembl gene	ENSG00000233529
Ensembl biotype	lncRNA
Entrez	102723346
RNAcentral	URS0000A776DB — lncRNA, 856 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000419481

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419481 — 3 exons

Exon	Start	End
ENSE00001614911	30954777	30954862
ENSE00001658514	30953067	30953204
ENSE00001687169	30945979	30946359

Expression profiles

Bgee: expression breadth broad, 88 present calls, max score 63.28.

Top tissues by expression

88 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle tissue	UBERON:0002385	63.28	gold quality
lower esophagus mucosa	UBERON:0035834	62.76	gold quality
skeletal muscle tissue	UBERON:0001134	59.16	gold quality
mucosa of stomach	UBERON:0001199	59.12	gold quality
gall bladder	UBERON:0002110	58.96	gold quality
stomach	UBERON:0000945	58.09	gold quality
body of stomach	UBERON:0001161	57.04	gold quality
endometrium	UBERON:0001295	55.95	gold quality
prefrontal cortex	UBERON:0000451	53.79	gold quality
esophagus mucosa	UBERON:0002469	53.36	gold quality
islet of Langerhans	UBERON:0000006	52.05	gold quality
esophagus	UBERON:0001043	51.11	gold quality
fundus of stomach	UBERON:0001160	51.07	gold quality
heart left ventricle	UBERON:0002084	50.92	gold quality
vermiform appendix	UBERON:0001154	50.20	gold quality
vagina	UBERON:0000996	49.78	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.34	gold quality
blood	UBERON:0000178	48.34	silver quality
muscle of leg	UBERON:0001383	48.12	gold quality
monocyte	CL:0000576	47.95	silver quality
body of pancreas	UBERON:0001150	47.76	gold quality
gastrocnemius	UBERON:0001388	47.05	gold quality
myometrium	UBERON:0001296	45.97	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.06	gold quality
multicellular organism	UBERON:0000468	44.76	gold quality
lung	UBERON:0002048	44.39	gold quality
upper lobe of left lung	UBERON:0008952	44.27	gold quality
adenohypophysis	UBERON:0002196	44.24	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.91	gold quality
cortex of kidney	UBERON:0001225	43.73	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.