HCG4

Summary

HCG4 (HLA complex group 4, HGNC:21241) is a unprocessed pseudogene on chromosome 6p22.1.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:21241
Approved symbol	HCG4
Name	HLA complex group 4
Location	6p22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	HCGIV-10, HCGIV.9
Ensembl gene	ENSG00000176998
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	54435
RNAcentral	URS000075DFE6 — lncRNA, 2083 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000418983

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418983 — 1 exons

Exon	Start	End
ENSE00001735745	29791753	29792750

Expression profiles

Bgee: expression breadth ubiquitous, 164 present calls, max score 75.37.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4387 / max 21.3684, expressed in 256 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
72478	0.4387	256

Top tissues by expression

272 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
amniotic fluid	UBERON:0000173	75.37	gold quality
adenohypophysis	UBERON:0002196	70.56	gold quality
pituitary gland	UBERON:0000007	70.25	gold quality
buccal mucosa cell	CL:0002336	68.17	gold quality
islet of Langerhans	UBERON:0000006	68.16	gold quality
tibia	UBERON:0000979	64.32	silver quality
right lobe of thyroid gland	UBERON:0001119	63.82	gold quality
pancreas	UBERON:0001264	63.52	gold quality
palpebral conjunctiva	UBERON:0001812	63.46	gold quality
right adrenal gland	UBERON:0001233	63.37	gold quality
lower esophagus mucosa	UBERON:0035834	63.06	gold quality
thyroid gland	UBERON:0002046	62.41	gold quality
left adrenal gland	UBERON:0001234	62.25	gold quality
nucleus accumbens	UBERON:0001882	62.16	gold quality
body of pancreas	UBERON:0001150	62.15	gold quality
left lobe of thyroid gland	UBERON:0001120	62.08	gold quality
right adrenal gland cortex	UBERON:0035827	61.94	gold quality
caput epididymis	UBERON:0004358	61.91	gold quality
left adrenal gland cortex	UBERON:0035825	61.59	gold quality
right atrium auricular region	UBERON:0006631	61.09	gold quality
right lung	UBERON:0002167	60.39	gold quality
right uterine tube	UBERON:0001302	60.38	gold quality
gall bladder	UBERON:0002110	60.19	gold quality
adrenal cortex	UBERON:0001235	60.17	gold quality
cardiac atrium	UBERON:0002081	60.13	gold quality
jejunal mucosa	UBERON:0000399	59.80	gold quality
fallopian tube	UBERON:0003889	59.45	gold quality
oviduct epithelium	UBERON:0004804	59.27	gold quality
prefrontal cortex	UBERON:0000451	59.21	gold quality
vagina	UBERON:0000996	58.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.