HCG4B

Summary

HCG4B (HLA complex group 4B, HGNC:22919) is a unprocessed pseudogene on chromosome 6p22.1.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:22919
Approved symbol	HCG4B
Name	HLA complex group 4B
Location	6p22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	HCGIV-6, HCGIV.5, HCGIV-06, bCX67J3.3, Em:AB023056.16, bPG309N1.1, bQB90C11.3
Ensembl gene	ENSG00000227262
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	80868
RNAcentral	URS000075A446 — lncRNA, 2624 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000450128

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450128 — 1 exons

Exon	Start	End
ENSE00001729327	29925983	29926973

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 72.93.

Top tissues by expression

281 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	72.93	gold quality
mucosa of transverse colon	UBERON:0004991	72.68	gold quality
small intestine Peyer’s patch	UBERON:0003454	69.38	gold quality
left ovary	UBERON:0002119	69.27	gold quality
right lobe of liver	UBERON:0001114	68.87	gold quality
ectocervix	UBERON:0012249	68.54	gold quality
endocervix	UBERON:0000458	67.72	gold quality
lower esophagus mucosa	UBERON:0035834	67.31	gold quality
mucosa of stomach	UBERON:0001199	67.24	gold quality
right uterine tube	UBERON:0001302	67.21	gold quality
small intestine	UBERON:0002108	67.14	gold quality
right ovary	UBERON:0002118	66.88	gold quality
right lung	UBERON:0002167	66.86	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.84	gold quality
left uterine tube	UBERON:0001303	66.66	gold quality
spleen	UBERON:0002106	66.26	gold quality
upper lobe of left lung	UBERON:0008952	66.20	gold quality
metanephros cortex	UBERON:0010533	66.00	gold quality
body of uterus	UBERON:0009853	65.88	gold quality
leukocyte	CL:0000738	65.37	gold quality
right coronary artery	UBERON:0001625	65.06	gold quality
transverse colon	UBERON:0001157	64.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.60	gold quality
descending thoracic aorta	UBERON:0002345	64.51	gold quality
monocyte	CL:0000576	64.37	gold quality
mononuclear cell	CL:0000842	64.24	gold quality
upper lobe of lung	UBERON:0008948	64.18	gold quality
body of stomach	UBERON:0001161	64.16	gold quality
ovary	UBERON:0000992	63.47	gold quality
pancreatic ductal cell	CL:0002079	63.08	silver quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	5667.43
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.