HCN4-AS1

Summary

HCN4-AS1 (HCN4 antisense RNA 1, HGNC:58475) is a long non-coding RNA gene on chromosome 15q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58475
Approved symbol	HCN4-AS1
Name	HCN4 antisense RNA 1
Location	15q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259650
Ensembl biotype	lncRNA
Entrez	141974275

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000557981, ENST00000558742

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000557981 — 3 exons

Exon	Start	End
ENSE00002537521	73335479	73335644
ENSE00002541562	73335276	73335332
ENSE00002555504	73342313	73342387

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 78.77.

Top tissues by expression

182 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	78.77	gold quality
cerebellar vermis	UBERON:0004720	78.47	silver quality
heart right ventricle	UBERON:0002080	78.27	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	74.79	gold quality
tendon of biceps brachii	UBERON:0008188	72.39	gold quality
vastus lateralis	UBERON:0001379	72.37	gold quality
buccal mucosa cell	CL:0002336	72.34	gold quality
skeletal muscle tissue	UBERON:0001134	72.20	gold quality
nasal cavity epithelium	UBERON:0005384	72.09	gold quality
tendon	UBERON:0000043	72.02	gold quality
ganglionic eminence	UBERON:0004023	71.46	gold quality
vena cava	UBERON:0004087	69.72	silver quality
bone marrow	UBERON:0002371	69.17	gold quality
cartilage tissue	UBERON:0002418	69.04	gold quality
superficial temporal artery	UBERON:0001614	68.98	gold quality
biceps brachii	UBERON:0001507	68.90	gold quality
blood	UBERON:0000178	68.88	gold quality
trabecular bone tissue	UBERON:0002483	67.25	gold quality
sperm	CL:0000019	66.75	gold quality
liver	UBERON:0002107	66.52	gold quality
superior frontal gyrus	UBERON:0002661	65.79	gold quality
postcentral gyrus	UBERON:0002581	65.62	gold quality
entorhinal cortex	UBERON:0002728	65.55	gold quality
nasal cavity mucosa	UBERON:0001826	65.40	gold quality
secondary oocyte	CL:0000655	65.17	gold quality
decidua	UBERON:0002450	65.05	gold quality
pons	UBERON:0000988	64.98	silver quality
parietal lobe	UBERON:0001872	64.80	gold quality
tibia	UBERON:0000979	64.63	gold quality
colonic mucosa	UBERON:0000317	64.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.