HDAC11-AS1

Summary

HDAC11-AS1 (HDAC11 antisense RNA 1, HGNC:40868) is a long non-coding RNA gene on chromosome 3p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40868
Approved symbol	HDAC11-AS1
Name	HDAC11 antisense RNA 1
Location	3p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244502
Ensembl biotype	lncRNA
Entrez	100874101
RNAcentral	URS000075E905 — lncRNA, 515 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424112

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424112 — 2 exons

Exon	Start	End
ENSE00004047410	13476979	13477085
ENSE00004047411	13479643	13480095

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 97.07.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8522 / max 22.6601, expressed in 304 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41192	0.8522	304

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.07	gold quality
bone marrow cell	CL:0002092	69.78	silver quality
right testis	UBERON:0004534	69.41	gold quality
left testis	UBERON:0004533	68.81	gold quality
testis	UBERON:0000473	68.34	gold quality
ganglionic eminence	UBERON:0004023	63.09	gold quality
bone marrow	UBERON:0002371	62.90	silver quality
skeletal muscle tissue	UBERON:0001134	58.45	gold quality
lower esophagus mucosa	UBERON:0035834	57.76	gold quality
lymph node	UBERON:0000029	57.39	gold quality
gall bladder	UBERON:0002110	57.18	gold quality
monocyte	CL:0000576	56.26	gold quality
leukocyte	CL:0000738	56.23	gold quality
prefrontal cortex	UBERON:0000451	56.11	gold quality
islet of Langerhans	UBERON:0000006	54.36	gold quality
muscle of leg	UBERON:0001383	52.69	gold quality
gastrocnemius	UBERON:0001388	52.26	gold quality
blood	UBERON:0000178	51.97	gold quality
vermiform appendix	UBERON:0001154	51.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	51.48	gold quality
placenta	UBERON:0001987	51.46	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.40	gold quality
apex of heart	UBERON:0002098	51.15	gold quality
urinary bladder	UBERON:0001255	51.04	gold quality
primary visual cortex	UBERON:0002436	50.54	gold quality
pancreas	UBERON:0001264	48.89	gold quality
adrenal tissue	UBERON:0018303	48.61	gold quality
right coronary artery	UBERON:0001625	48.10	gold quality
heart left ventricle	UBERON:0002084	47.99	gold quality
adult mammalian kidney	UBERON:0000082	47.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.