HDAC3-AS1

Summary

HDAC3-AS1 (HDAC3 antisense RNA 1, HGNC:40178) is a long non-coding RNA gene on chromosome 5q31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40178
Approved symbol	HDAC3-AS1
Name	HDAC3 antisense RNA 1
Location	5q31.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228737
Ensembl biotype	lncRNA
Entrez	145432493

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000422040, ENST00000758090

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422040 — 3 exons

Exon	Start	End
ENSE00001666595	141626056	141626481
ENSE00001710669	141618414	141618489
ENSE00001802710	141625847	141625965

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 90.31.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.31	gold quality
colonic epithelium	UBERON:0000397	72.50	gold quality
ventricular zone	UBERON:0003053	70.49	gold quality
sural nerve	UBERON:0015488	67.64	silver quality
skeletal muscle tissue	UBERON:0001134	65.58	gold quality
bone marrow cell	CL:0002092	64.75	silver quality
granulocyte	CL:0000094	64.04	gold quality
right adrenal gland cortex	UBERON:0035827	62.76	gold quality
muscle tissue	UBERON:0002385	62.68	gold quality
blood	UBERON:0000178	62.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.97	gold quality
islet of Langerhans	UBERON:0000006	61.90	gold quality
right adrenal gland	UBERON:0001233	61.66	gold quality
duodenum	UBERON:0002114	61.48	gold quality
left adrenal gland	UBERON:0001234	61.24	gold quality
ganglionic eminence	UBERON:0004023	61.13	gold quality
adrenal gland	UBERON:0002369	60.95	gold quality
left adrenal gland cortex	UBERON:0035825	60.83	gold quality
bone marrow	UBERON:0002371	60.78	gold quality
left lobe of thyroid gland	UBERON:0001120	60.63	gold quality
body of pancreas	UBERON:0001150	60.62	gold quality
thyroid gland	UBERON:0002046	60.42	gold quality
cortex of kidney	UBERON:0001225	60.13	gold quality
right lobe of thyroid gland	UBERON:0001119	60.02	gold quality
vermiform appendix	UBERON:0001154	59.80	gold quality
metanephros cortex	UBERON:0010533	59.77	gold quality
endometrium	UBERON:0001295	59.73	gold quality
tonsil	UBERON:0002372	59.67	gold quality
liver	UBERON:0002107	59.58	gold quality
lymph node	UBERON:0000029	59.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.