HDAC4-AS2

Summary

HDAC4-AS2 (HDAC4 antisense RNA 2, HGNC:58134) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58134
Approved symbol	HDAC4-AS2
Name	HDAC4 antisense RNA 2
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	meloe
Ensembl gene	ENSG00000287405
Ensembl biotype	lncRNA
Entrez	138842259
RNAcentral	URS0000EF46F5 — lncRNA, 3352 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000653060

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000653060 — 2 exons

Exon	Start	End
ENSE00003858744	239194118	239194176
ENSE00003865210	239194362	239197654

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 76.88.

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	76.88	gold quality
bone marrow cell	CL:0002092	71.16	silver quality
colonic epithelium	UBERON:0000397	66.07	silver quality
sural nerve	UBERON:0015488	64.03	gold quality
urinary bladder	UBERON:0001255	61.01	silver quality
hindlimb stylopod muscle	UBERON:0004252	59.58	gold quality
bone marrow	UBERON:0002371	59.45	silver quality
corpus callosum	UBERON:0002336	57.42	gold quality
tonsil	UBERON:0002372	56.59	silver quality
cortex of kidney	UBERON:0001225	55.45	gold quality
ganglionic eminence	UBERON:0004023	55.27	silver quality
blood	UBERON:0000178	54.59	gold quality
monocyte	CL:0000576	52.41	silver quality
muscle of leg	UBERON:0001383	51.99	gold quality
liver	UBERON:0002107	51.98	silver quality
gastrocnemius	UBERON:0001388	51.87	gold quality
prefrontal cortex	UBERON:0000451	51.67	gold quality
small intestine	UBERON:0002108	49.49	gold quality
tibial nerve	UBERON:0001323	49.19	gold quality
granulocyte	CL:0000094	49.01	silver quality
thoracic mammary gland	UBERON:0005200	48.75	silver quality
pancreas	UBERON:0001264	48.55	silver quality
islet of Langerhans	UBERON:0000006	48.08	silver quality
primary visual cortex	UBERON:0002436	48.00	silver quality
adrenal tissue	UBERON:0018303	47.60	silver quality
myometrium	UBERON:0001296	47.26	silver quality
frontal cortex	UBERON:0001870	47.10	gold quality
thyroid gland	UBERON:0002046	46.67	gold quality
putamen	UBERON:0001874	46.52	gold quality
calcaneal tendon	UBERON:0003701	46.48	silver quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.