HDAC4-AS3

Summary

HDAC4-AS3 (HDAC4 antisense RNA 3, HGNC:58397) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58397
Approved symbol	HDAC4-AS3
Name	HDAC4 antisense RNA 3
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286307
Ensembl biotype	lncRNA
Entrez	141725168

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000656551

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000656551 — 2 exons

Exon	Start	End
ENSE00003876639	239117684	239118842
ENSE00003888314	239114858	239116212

Expression profiles

Bgee: expression breadth broad, 88 present calls, max score 72.15.

Top tissues by expression

88 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	72.15	gold quality
bone marrow cell	CL:0002092	70.04	silver quality
skeletal muscle tissue	UBERON:0001134	67.27	gold quality
liver	UBERON:0002107	66.02	silver quality
urinary bladder	UBERON:0001255	62.83	silver quality
tonsil	UBERON:0002372	61.79	silver quality
bone marrow	UBERON:0002371	60.07	silver quality
myometrium	UBERON:0001296	58.01	silver quality
hindlimb stylopod muscle	UBERON:0004252	57.72	gold quality
ganglionic eminence	UBERON:0004023	57.69	silver quality
blood	UBERON:0000178	54.23	gold quality
thyroid gland	UBERON:0002046	51.70	silver quality
prefrontal cortex	UBERON:0000451	50.21	gold quality
small intestine	UBERON:0002108	49.63	silver quality
pancreas	UBERON:0001264	49.39	gold quality
adrenal tissue	UBERON:0018303	49.19	silver quality
muscle of leg	UBERON:0001383	48.93	gold quality
lower esophagus mucosa	UBERON:0035834	48.81	gold quality
monocyte	CL:0000576	48.79	silver quality
gastrocnemius	UBERON:0001388	48.39	gold quality
cerebellum	UBERON:0002037	47.79	silver quality
cerebellar cortex	UBERON:0002129	47.62	silver quality
cerebellar hemisphere	UBERON:0002245	47.46	silver quality
islet of Langerhans	UBERON:0000006	47.37	gold quality
lung	UBERON:0002048	47.04	silver quality
thoracic mammary gland	UBERON:0005200	46.94	silver quality
right hemisphere of cerebellum	UBERON:0014890	46.89	silver quality
adrenal gland	UBERON:0002369	46.88	silver quality
uterine cervix	UBERON:0000002	46.61	silver quality
heart left ventricle	UBERON:0002084	46.15	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.