HDHD5-AS1

Summary

HDHD5-AS1 (HDHD5 antisense RNA 1, HGNC:1842) is a long non-coding RNA gene on chromosome 22q11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1842
Approved symbol	HDHD5-AS1
Name	HDHD5 antisense RNA 1
Location	22q11.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00017
Ensembl gene	ENSG00000185837
Ensembl biotype	lncRNA
Entrez	100130717
RNAcentral	URS000075A859 — lncRNA, 650 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000329743, ENST00000431923, ENST00000689229, ENST00000815345

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000329743 — 2 exons

Exon	Start	End
ENSE00004217232	17165269	17165451
ENSE00004217238	17159340	17159551

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 94.01.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0417 / max 17.4796, expressed in 576 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190958	1.0417	576

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	94.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.30	gold quality
ventricular zone	UBERON:0003053	71.99	gold quality
right uterine tube	UBERON:0001302	69.86	gold quality
adenohypophysis	UBERON:0002196	69.14	gold quality
left adrenal gland cortex	UBERON:0035825	68.69	gold quality
ganglionic eminence	UBERON:0004023	68.31	gold quality
left adrenal gland	UBERON:0001234	67.85	gold quality
left lobe of thyroid gland	UBERON:0001120	67.44	gold quality
right lobe of thyroid gland	UBERON:0001119	67.43	gold quality
right adrenal gland cortex	UBERON:0035827	67.25	gold quality
pituitary gland	UBERON:0000007	66.91	gold quality
stromal cell of endometrium	CL:0002255	66.89	gold quality
right adrenal gland	UBERON:0001233	66.55	gold quality
cerebellar hemisphere	UBERON:0002245	66.50	gold quality
thyroid gland	UBERON:0002046	66.48	gold quality
cerebellar cortex	UBERON:0002129	66.45	gold quality
adrenal cortex	UBERON:0001235	66.43	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.37	gold quality
cortical plate	UBERON:0005343	66.15	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.81	gold quality
caudate nucleus	UBERON:0001873	65.68	gold quality
hypothalamus	UBERON:0001898	65.63	gold quality
putamen	UBERON:0001874	65.60	gold quality
adrenal gland	UBERON:0002369	65.35	gold quality
adult mammalian kidney	UBERON:0000082	65.33	gold quality
anterior cingulate cortex	UBERON:0009835	65.18	gold quality
left ovary	UBERON:0002119	64.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.