HEATR3-AS1

Summary

HEATR3-AS1 (HEATR3 antisense RNA 1, HGNC:55406) is a long non-coding RNA gene on chromosome 16q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55406
Approved symbol	HEATR3-AS1
Name	HEATR3 antisense RNA 1
Location	16q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259843
Ensembl biotype	lncRNA
Entrez	120017339
RNAcentral	URS00026A1A9E — lncRNA, 3187 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000568130, ENST00000719503, ENST00000719504, ENST00000719505, ENST00000719506, ENST00000719507

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000568130 — 3 exons

Exon	Start	End
ENSE00002617099	50064691	50064807
ENSE00004037275	50066053	50066315
ENSE00004037285	50046246	50046637

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 70.75.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	70.75	gold quality
ganglionic eminence	UBERON:0004023	67.17	gold quality
liver	UBERON:0002107	66.25	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.63	gold quality
lymph node	UBERON:0000029	57.06	gold quality
islet of Langerhans	UBERON:0000006	55.31	gold quality
stromal cell of endometrium	CL:0002255	55.27	gold quality
prefrontal cortex	UBERON:0000451	55.23	gold quality
leukocyte	CL:0000738	54.64	silver quality
placenta	UBERON:0001987	54.50	gold quality
monocyte	CL:0000576	53.83	silver quality
blood	UBERON:0000178	52.68	silver quality
primary visual cortex	UBERON:0002436	51.33	gold quality
cortex of kidney	UBERON:0001225	50.51	gold quality
muscle of leg	UBERON:0001383	50.13	gold quality
fundus of stomach	UBERON:0001160	49.96	gold quality
gastrocnemius	UBERON:0001388	49.38	gold quality
superior frontal gyrus	UBERON:0002661	48.81	gold quality
right lobe of thyroid gland	UBERON:0001119	47.09	gold quality
pancreas	UBERON:0001264	46.90	gold quality
heart left ventricle	UBERON:0002084	46.54	silver quality
frontal cortex	UBERON:0001870	46.52	gold quality
temporal lobe	UBERON:0001871	45.91	gold quality
Ammon’s horn	UBERON:0001954	45.83	gold quality
cerebellum	UBERON:0002037	45.60	silver quality
cerebral cortex	UBERON:0000956	45.47	gold quality
substantia nigra	UBERON:0002038	45.27	gold quality
stomach	UBERON:0000945	45.24	gold quality
endometrium	UBERON:0001295	45.18	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.