HEATR6-DT

Summary

HEATR6-DT (HEATR6 divergent transcript, HGNC:52929) is a long non-coding RNA gene on chromosome 17q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52929
Approved symbol	HEATR6-DT
Name	HEATR6 divergent transcript
Location	17q23.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC025048.4
Ensembl gene	ENSG00000267416
Ensembl biotype	lncRNA
Entrez	105371849
RNAcentral	URS0000A76B7C — lncRNA, 712 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000589740, ENST00000688367, ENST00000810065, ENST00000810066

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000589740 — 2 exons

Exon	Start	End
ENSE00004206563	60088161	60088713
ENSE00004206566	60078946	60079472

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 78.72.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.72	silver quality
stromal cell of endometrium	CL:0002255	74.33	gold quality
spleen	UBERON:0002106	67.77	gold quality
skeletal muscle tissue	UBERON:0001134	67.31	gold quality
vermiform appendix	UBERON:0001154	66.73	gold quality
lymph node	UBERON:0000029	66.50	gold quality
ventricular zone	UBERON:0003053	64.93	gold quality
granulocyte	CL:0000094	64.49	gold quality
esophagus mucosa	UBERON:0002469	64.48	gold quality
blood	UBERON:0000178	64.14	gold quality
right lung	UBERON:0002167	64.05	gold quality
tonsil	UBERON:0002372	63.68	gold quality
skin of leg	UBERON:0001511	63.36	gold quality
leukocyte	CL:0000738	63.32	gold quality
minor salivary gland	UBERON:0001830	63.03	gold quality
saliva-secreting gland	UBERON:0001044	62.97	gold quality
monocyte	CL:0000576	62.96	gold quality
zone of skin	UBERON:0000014	62.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.79	gold quality
ganglionic eminence	UBERON:0004023	62.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.01	gold quality
skin of abdomen	UBERON:0001416	61.94	gold quality
gall bladder	UBERON:0002110	61.27	gold quality
rectum	UBERON:0001052	61.16	gold quality
upper lobe of left lung	UBERON:0008952	61.04	gold quality
cortical plate	UBERON:0005343	60.49	gold quality
esophagus	UBERON:0001043	59.64	gold quality
lung	UBERON:0002048	59.56	gold quality
bone marrow	UBERON:0002371	59.22	gold quality
smooth muscle tissue	UBERON:0001135	58.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.84

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.