HECW1-IT1

Summary

HECW1-IT1 (HECW1 intronic transcript 1, HGNC:41465) is a long non-coding RNA gene on chromosome 7p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41465
Approved symbol	HECW1-IT1
Name	HECW1 intronic transcript 1
Location	7p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000181211
Ensembl biotype	lncRNA
Entrez	100127950
RNAcentral	URS000060D97F — lncRNA, 1839 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000322220, ENST00000770632

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000322220 — 7 exons

Exon	Start	End
ENSE00001243294	43162926	43163187
ENSE00001243302	43161610	43161715
ENSE00001243311	43148641	43148827
ENSE00001243318	43147448	43147585
ENSE00001243324	43121803	43122019
ENSE00001243330	43118947	43119195
ENSE00001243340	43117896	43118575

Expression profiles

Bgee: expression breadth broad, 14 present calls, max score 86.59.

Top tissues by expression

164 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.59	gold quality
calcaneal tendon	UBERON:0003701	52.80	gold quality
upper lobe of lung	UBERON:0008948	50.96	silver quality
lower lobe of lung	UBERON:0008949	50.71	silver quality
corpus callosum	UBERON:0002336	47.00	silver quality
prefrontal cortex	UBERON:0000451	46.69	silver quality
right testis	UBERON:0004534	45.96	gold quality
left testis	UBERON:0004533	44.80	gold quality
testis	UBERON:0000473	44.62	gold quality
tendon	UBERON:0000043	44.41	silver quality
lung	UBERON:0002048	43.42	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
blood	UBERON:0000178	42.11	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
trigeminal ganglion	UBERON:0001675	41.37	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
middle temporal gyrus	UBERON:0002771	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
cardiac ventricle	UBERON:0002082	41.15	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
prostate gland	UBERON:0002367	41.12	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
anatomical system	UBERON:0000467	41.00	silver quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
liver	UBERON:0002107	40.89	gold quality
putamen	UBERON:0001874	40.87	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.