HECW2-AS1

Summary

HECW2-AS1 (HECW2 antisense RNA 1, HGNC:54062) is a long non-coding RNA gene on chromosome 2q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54062
Approved symbol	HECW2-AS1
Name	HECW2 antisense RNA 1
Location	2q32.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229056
Ensembl biotype	lncRNA
Entrez	101927482
RNAcentral	URS000075D97D — lncRNA, 1424 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000430904, ENST00000433933, ENST00000605907, ENST00000748258

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430904 — 3 exons

Exon	Start	End
ENSE00001749456	196260331	196260372
ENSE00004090884	196263051	196264204
ENSE00004090885	196260019	196260240

Expression profiles

Bgee: expression breadth ubiquitous, 143 present calls, max score 80.32.

FANTOM5 (CAGE): breadth broad, TPM avg 1.8601 / max 788.4400, expressed in 287 samples.

FANTOM5 promoters (13 alternative TSS)

Promoter ID	TPM avg	Samples expressed
24449	0.4584	92
24452	0.3804	63
24448	0.3404	85
24447	0.1832	65
24451	0.1232	34
24446	0.1225	45
24454	0.0795	5
24455	0.0626	19
24453	0.0455	11
24458	0.0245	6

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	80.32	gold quality
prostate gland	UBERON:0002367	78.67	gold quality
bone marrow cell	CL:0002092	73.30	gold quality
stromal cell of endometrium	CL:0002255	71.00	gold quality
leukocyte	CL:0000738	70.90	gold quality
monocyte	CL:0000576	70.61	gold quality
colonic epithelium	UBERON:0000397	70.59	silver quality
right adrenal gland cortex	UBERON:0035827	70.02	gold quality
right adrenal gland	UBERON:0001233	69.47	gold quality
lymph node	UBERON:0000029	69.46	gold quality
granulocyte	CL:0000094	69.33	gold quality
placenta	UBERON:0001987	69.18	gold quality
rectum	UBERON:0001052	69.17	gold quality
left adrenal gland cortex	UBERON:0035825	69.11	gold quality
gall bladder	UBERON:0002110	68.99	gold quality
adrenal cortex	UBERON:0001235	67.20	gold quality
jejunal mucosa	UBERON:0000399	67.19	gold quality
left adrenal gland	UBERON:0001234	66.84	gold quality
adrenal gland	UBERON:0002369	66.55	gold quality
vermiform appendix	UBERON:0001154	65.44	gold quality
smooth muscle tissue	UBERON:0001135	65.27	gold quality
small intestine Peyer’s patch	UBERON:0003454	64.31	gold quality
ventricular zone	UBERON:0003053	64.09	gold quality
small intestine	UBERON:0002108	63.76	gold quality
mucosa of transverse colon	UBERON:0004991	63.18	gold quality
caecum	UBERON:0001153	59.97	gold quality
blood	UBERON:0000178	57.14	gold quality
ileal mucosa	UBERON:0000331	57.13	gold quality
islet of Langerhans	UBERON:0000006	56.86	gold quality
calcaneal tendon	UBERON:0003701	56.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.