HELZ-AS1

Summary

HELZ-AS1 (HELZ antisense RNA 1, HGNC:55319) is a long non-coding RNA gene on chromosome 17q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55319
Approved symbol	HELZ-AS1
Name	HELZ antisense RNA 1
Location	17q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266473
Ensembl biotype	lncRNA
Entrez	101928021
RNAcentral	URS0000A7685A — lncRNA, 850 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 46 — 46 lncRNA

ENST00000583452, ENST00000585193, ENST00000650446, ENST00000717273, ENST00000717274, ENST00000717275, ENST00000717276, ENST00000717277, ENST00000717278, ENST00000717279, ENST00000753914, ENST00000753915, ENST00000753916, ENST00000753917, ENST00000753918, ENST00000753919, ENST00000753920, ENST00000753921, ENST00000753922, ENST00000753923, ENST00000753924, ENST00000753925, ENST00000753926, ENST00000753927, ENST00000753928, ENST00000753929, ENST00000753930, ENST00000753931, ENST00000753932, ENST00000753933, ENST00000753934, ENST00000753935, ENST00000753936, ENST00000753937, ENST00000753938, ENST00000753939, ENST00000753940, ENST00000753941, ENST00000753942, ENST00000753943, ENST00000753944, ENST00000753945, ENST00000753946, ENST00000753947, ENST00000753948, ENST00000753949

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000583452 — 2 exons

Exon	Start	End
ENSE00002727561	67225287	67225541
ENSE00004032099	67224303	67224427

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 81.70.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.70	gold quality
thymus	UBERON:0002370	72.06	silver quality
right testis	UBERON:0004534	69.65	gold quality
left testis	UBERON:0004533	68.93	gold quality
sural nerve	UBERON:0015488	68.20	gold quality
ventricular zone	UBERON:0003053	67.96	gold quality
testis	UBERON:0000473	67.79	gold quality
quadriceps femoris	UBERON:0001377	65.49	gold quality
cerebellar vermis	UBERON:0004720	64.61	gold quality
granulocyte	CL:0000094	63.27	gold quality
metanephros cortex	UBERON:0010533	63.17	gold quality
monocyte	CL:0000576	62.55	gold quality
kidney	UBERON:0002113	62.23	gold quality
adult mammalian kidney	UBERON:0000082	61.79	gold quality
right lobe of liver	UBERON:0001114	61.07	gold quality
cortex of kidney	UBERON:0001225	61.03	gold quality
liver	UBERON:0002107	60.86	gold quality
blood	UBERON:0000178	60.39	gold quality
ganglionic eminence	UBERON:0004023	59.81	gold quality
cortical plate	UBERON:0005343	58.02	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.94	gold quality
skeletal muscle tissue	UBERON:0001134	57.58	gold quality
apex of heart	UBERON:0002098	57.54	gold quality
urinary bladder	UBERON:0001255	56.98	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.75	gold quality
stromal cell of endometrium	CL:0002255	56.54	gold quality
right adrenal gland cortex	UBERON:0035827	56.23	gold quality
muscle tissue	UBERON:0002385	55.96	gold quality
nucleus accumbens	UBERON:0001882	55.46	gold quality
right lung	UBERON:0002167	55.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.