HEXD-IT1

Summary

HEXD-IT1 (HEXD intronic transcript 1, HGNC:43650) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43650
Approved symbol	HEXD-IT1
Name	HEXD intronic transcript 1
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000279066
Ensembl biotype	lncRNA
Entrez	100505970
RNAcentral	URS0002123132 — lncRNA, 1280 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000624980

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000624980 — 1 exons

Exon	Start	End
ENSE00003755722	82425498	82427310

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 79.47.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4111 / max 313.1952, expressed in 18 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
163516	0.4111	18

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.47	gold quality
colonic epithelium	UBERON:0000397	67.76	silver quality
sural nerve	UBERON:0015488	66.86	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.47	silver quality
bone marrow cell	CL:0002092	64.12	silver quality
skeletal muscle tissue	UBERON:0001134	60.85	gold quality
cortical plate	UBERON:0005343	60.63	silver quality
bone marrow	UBERON:0002371	60.36	gold quality
blood	UBERON:0000178	60.35	gold quality
tonsil	UBERON:0002372	59.57	gold quality
stromal cell of endometrium	CL:0002255	59.04	gold quality
metanephros cortex	UBERON:0010533	58.29	gold quality
monocyte	CL:0000576	57.84	gold quality
muscle tissue	UBERON:0002385	57.46	gold quality
cortex of kidney	UBERON:0001225	57.26	gold quality
left ovary	UBERON:0002119	57.03	gold quality
urinary bladder	UBERON:0001255	56.96	gold quality
ganglionic eminence	UBERON:0004023	56.93	silver quality
cerebellum	UBERON:0002037	56.86	gold quality
cerebellar hemisphere	UBERON:0002245	56.82	gold quality
cerebellar cortex	UBERON:0002129	56.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.61	gold quality
endometrium	UBERON:0001295	56.58	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.56	gold quality
ovary	UBERON:0000992	56.48	gold quality
right uterine tube	UBERON:0001302	56.44	gold quality
liver	UBERON:0002107	56.24	silver quality
granulocyte	CL:0000094	56.13	gold quality
body of pancreas	UBERON:0001150	55.42	gold quality
right ovary	UBERON:0002118	55.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.20

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.