HIPK1-AS1

Summary

HIPK1-AS1 (HIPK1 antisense RNA 1, HGNC:50576) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50576
Approved symbol	HIPK1-AS1
Name	HIPK1 antisense RNA 1
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235527
Ensembl biotype	lncRNA
Entrez	101928846
RNAcentral	URS000075BAF8 — lncRNA, 2125 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 11 lncRNA, 2 retained_intron

ENST00000426237, ENST00000427953, ENST00000441071, ENST00000450706, ENST00000653365, ENST00000670954, ENST00000722334, ENST00000722335, ENST00000722336, ENST00000722337, ENST00000722338, ENST00000722339, ENST00000722340

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426237 — 2 exons

Exon	Start	End
ENSE00004042898	113927635	113928388
ENSE00004042899	113929209	113929518

Expression profiles

Bgee: expression breadth ubiquitous, 177 present calls, max score 84.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1504 / max 13.2807, expressed in 61 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13925	0.1504	61

Top tissues by expression

220 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superficial temporal artery	UBERON:0001614	84.52	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.88	gold quality
bone marrow cell	CL:0002092	74.38	gold quality
right testis	UBERON:0004534	71.58	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	71.57	gold quality
tendon of biceps brachii	UBERON:0008188	71.18	silver quality
left testis	UBERON:0004533	71.07	gold quality
testis	UBERON:0000473	69.18	gold quality
lower lobe of lung	UBERON:0008949	67.63	silver quality
gingival epithelium	UBERON:0001949	66.13	gold quality
epithelium of nasopharynx	UBERON:0001951	65.77	silver quality
right uterine tube	UBERON:0001302	64.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	64.52	gold quality
putamen	UBERON:0001874	63.75	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.55	gold quality
spinal cord	UBERON:0002240	63.21	gold quality
buccal mucosa cell	CL:0002336	63.16	silver quality
mucosa of paranasal sinus	UBERON:0005030	62.95	silver quality
germinal epithelium of ovary	UBERON:0001304	62.78	silver quality
amygdala	UBERON:0001876	62.60	gold quality
substantia nigra	UBERON:0002038	62.34	gold quality
corpus callosum	UBERON:0002336	62.23	gold quality
midbrain	UBERON:0001891	62.06	gold quality
cardia of stomach	UBERON:0001162	62.03	gold quality
prefrontal cortex	UBERON:0000451	61.86	gold quality
gingiva	UBERON:0001828	61.30	gold quality
vena cava	UBERON:0004087	61.30	silver quality
medial globus pallidus	UBERON:0002477	61.02	silver quality
islet of Langerhans	UBERON:0000006	60.90	gold quality
nucleus accumbens	UBERON:0001882	60.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.