HLMR1

Summary

HLMR1 (hepatic lncRNA metabolic regulator 1, HGNC:56713) is a long non-coding RNA gene on chromosome 3q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56713
Approved symbol	HLMR1
Name	hepatic lncRNA metabolic regulator 1
Location	3q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243818
Ensembl biotype	lncRNA
Entrez	100507389
RNAcentral	URS000075A7B9 — lncRNA, 1827 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000476385, ENST00000479792, ENST00000654729, ENST00000655382, ENST00000655467, ENST00000656965, ENST00000657885, ENST00000658594, ENST00000658642, ENST00000659017, ENST00000661944, ENST00000662125, ENST00000663511, ENST00000664203, ENST00000665496, ENST00000666651, ENST00000668368, ENST00000668430, ENST00000669437, ENST00000670740, ENST00000671570, ENST00000700987, ENST00000769319, ENST00000769320

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000476385 — 5 exons

Exon	Start	End
ENSE00001827369	142933205	142933268
ENSE00001849625	142938475	142938653
ENSE00001871313	142941399	142942534
ENSE00001883891	142926675	142926896
ENSE00001894651	142936423	142936646

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 91.44.

Top tissues by expression

183 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	91.44	gold quality
liver	UBERON:0002107	91.00	gold quality
ventricular zone	UBERON:0003053	62.78	gold quality
anterior cingulate cortex	UBERON:0009835	61.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.45	silver quality
ganglionic eminence	UBERON:0004023	56.92	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
skin of hip	UBERON:0001554	53.77	silver quality
endothelial cell	CL:0000115	53.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.97	silver quality
leukocyte	CL:0000738	51.90	silver quality
monocyte	CL:0000576	51.10	silver quality
cerebellar vermis	UBERON:0004720	48.63	gold quality
prefrontal cortex	UBERON:0000451	48.50	gold quality
vermiform appendix	UBERON:0001154	47.55	gold quality
muscle of leg	UBERON:0001383	47.41	silver quality
adult mammalian kidney	UBERON:0000082	46.87	gold quality
upper leg skin	UBERON:0004262	46.58	silver quality
gastrocnemius	UBERON:0001388	46.01	silver quality
lymph node	UBERON:0000029	45.96	silver quality
blood	UBERON:0000178	45.69	gold quality
synovial joint	UBERON:0002217	44.48	silver quality
right atrium auricular region	UBERON:0006631	44.38	gold quality
medial globus pallidus	UBERON:0002477	44.35	silver quality
adrenal tissue	UBERON:0018303	44.07	silver quality
placenta	UBERON:0001987	44.05	gold quality
cardiac atrium	UBERON:0002081	44.03	gold quality
heart left ventricle	UBERON:0002084	43.95	silver quality
heart	UBERON:0000948	43.93	gold quality
right lobe of thyroid gland	UBERON:0001119	43.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.