HLTF-AS1

Summary

HLTF-AS1 (HLTF antisense RNA 1, HGNC:40554) is a long non-coding RNA gene on chromosome 3q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40554
Approved symbol	HLTF-AS1
Name	HLTF antisense RNA 1
Location	3q24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239718
Ensembl biotype	lncRNA
Entrez	100873945
RNAcentral	URS00002A9F40 — lncRNA, 415 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000492461

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000492461 — 3 exons

Exon	Start	End
ENSE00001888893	149102587	149102823
ENSE00001925379	149099501	149099531
ENSE00001944935	149086332	149086478

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 84.45.

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	84.45	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.51	silver quality
testis	UBERON:0000473	70.06	gold quality
ganglionic eminence	UBERON:0004023	68.97	gold quality
ventricular zone	UBERON:0003053	68.71	gold quality
lung	UBERON:0002048	68.59	gold quality
bone marrow cell	CL:0002092	67.50	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.32	gold quality
adrenal gland	UBERON:0002369	66.76	gold quality
urinary bladder	UBERON:0001255	66.01	silver quality
liver	UBERON:0002107	65.46	silver quality
stromal cell of endometrium	CL:0002255	65.11	gold quality
temporal lobe	UBERON:0001871	64.42	gold quality
cortex of kidney	UBERON:0001225	63.16	gold quality
pancreas	UBERON:0001264	62.70	silver quality
heart	UBERON:0000948	62.05	gold quality
prefrontal cortex	UBERON:0000451	59.69	gold quality
frontal cortex	UBERON:0001870	59.65	gold quality
blood	UBERON:0000178	58.61	gold quality
kidney	UBERON:0002113	57.51	gold quality
brain	UBERON:0000955	57.24	gold quality
endometrium	UBERON:0001295	56.20	gold quality
tonsil	UBERON:0002372	56.00	silver quality
cerebellum	UBERON:0002037	55.97	gold quality
superior frontal gyrus	UBERON:0002661	55.84	gold quality
smooth muscle tissue	UBERON:0001135	55.81	gold quality
stomach	UBERON:0000945	55.67	gold quality
primary visual cortex	UBERON:0002436	53.45	gold quality
adult mammalian kidney	UBERON:0000082	53.35	gold quality
cerebellar cortex	UBERON:0002129	52.43	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.