HLX-AS1

Summary

HLX-AS1 (HLX antisense RNA 1, HGNC:42509) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42509
Approved symbol	HLX-AS1
Name	HLX antisense RNA 1
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257551
Ensembl biotype	lncRNA
Entrez	100873924
RNAcentral	URS00004C2BF8 — lncRNA, 563 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000552026, ENST00000691443, ENST00000777346, ENST00000777449, ENST00000777450, ENST00000777451, ENST00000777452, ENST00000777453

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000552026 — 3 exons

Exon	Start	End
ENSE00002335495	220832763	220832858
ENSE00002358465	220833018	220833192
ENSE00002385781	220879849	220880140

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 73.26.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	73.26	gold quality
skeletal muscle tissue	UBERON:0001134	68.40	gold quality
bone marrow cell	CL:0002092	66.23	silver quality
hindlimb stylopod muscle	UBERON:0004252	65.86	gold quality
ventricular zone	UBERON:0003053	65.83	gold quality
popliteal artery	UBERON:0002250	63.59	gold quality
tibial artery	UBERON:0007610	63.58	gold quality
stromal cell of endometrium	CL:0002255	63.34	gold quality
muscle of leg	UBERON:0001383	60.79	gold quality
right coronary artery	UBERON:0001625	60.65	gold quality
gall bladder	UBERON:0002110	60.19	gold quality
bone marrow	UBERON:0002371	59.78	gold quality
left coronary artery	UBERON:0001626	59.64	gold quality
gastrocnemius	UBERON:0001388	59.59	gold quality
monocyte	CL:0000576	58.82	gold quality
prefrontal cortex	UBERON:0000451	58.16	gold quality
lymph node	UBERON:0000029	58.14	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.76	gold quality
urinary bladder	UBERON:0001255	57.44	gold quality
calcaneal tendon	UBERON:0003701	56.80	gold quality
blood	UBERON:0000178	55.30	gold quality
sural nerve	UBERON:0015488	55.00	silver quality
subcutaneous adipose tissue	UBERON:0002190	54.45	gold quality
adipose tissue	UBERON:0001013	54.07	gold quality
descending thoracic aorta	UBERON:0002345	53.87	gold quality
duodenum	UBERON:0002114	53.67	gold quality
Ammon’s horn	UBERON:0001954	53.65	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	53.63	gold quality
omental fat pad	UBERON:0010414	53.53	gold quality
islet of Langerhans	UBERON:0000006	53.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.