HMX1-AS1

Summary

HMX1-AS1 (HMX1 antisense RNA 1, HGNC:58730) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58730
Approved symbol	HMX1-AS1
Name	HMX1 antisense RNA 1
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258507
Ensembl biotype	lncRNA
Entrez	143433678

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000557144

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000557144 — 2 exons

Exon	Start	End
ENSE00002523240	8858715	8859097
ENSE00002532736	8860649	8860827

Expression profiles

Bgee: expression breadth broad, 26 present calls, max score 51.17.

Top tissues by expression

26 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
prefrontal cortex	UBERON:0000451	51.17	gold quality
primary visual cortex	UBERON:0002436	47.67	silver quality
blood	UBERON:0000178	43.12	silver quality
cerebral cortex	UBERON:0000956	42.66	gold quality
putamen	UBERON:0001874	42.26	silver quality
Ammon’s horn	UBERON:0001954	41.57	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.37	silver quality
substantia nigra	UBERON:0002038	41.23	silver quality
brain	UBERON:0000955	41.22	gold quality
amygdala	UBERON:0001876	41.22	silver quality
adrenal tissue	UBERON:0018303	41.15	silver quality
right frontal lobe	UBERON:0002810	40.91	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	40.60	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	40.45	silver quality
caudate nucleus	UBERON:0001873	40.14	silver quality
hypothalamus	UBERON:0001898	40.07	gold quality
esophagus	UBERON:0001043	39.57	silver quality
transverse colon	UBERON:0001157	39.16	silver quality
muscle layer of sigmoid colon	UBERON:0035805	38.87	silver quality
nucleus accumbens	UBERON:0001882	38.23	silver quality
body of stomach	UBERON:0001161	37.95	silver quality
anterior cingulate cortex	UBERON:0009835	36.11	silver quality
pituitary gland	UBERON:0000007	34.84	silver quality
right testis	UBERON:0004534	33.12	silver quality
testis	UBERON:0000473	32.46	silver quality
left testis	UBERON:0004533	31.26	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.