HNRNPLL

Summary

HNRNPLL (heterogeneous nuclear ribonucleoprotein L like, HGNC:25127) is a protein-coding gene on chromosome 2p22.1, encoding Heterogeneous nuclear ribonucleoprotein L-like (Q8WVV9). RNA-binding protein that functions as a regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A.

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).

Source: NCBI Gene 92906 — RefSeq curated summary.

At a glance

• GWAS associations: 1
• Clinical variants (ClinVar): 60 total
• Druggable target: yes
• MANE Select transcript: NM_138394

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:25127
Approved symbol	HNRNPLL
Name	heterogeneous nuclear ribonucleoprotein L like
Location	2p22.1
Locus type	gene with protein product
Status	Approved
Ensembl gene	ENSG00000143889
Ensembl biotype	protein_coding
OMIM	611208
Entrez	92906

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 9 protein_coding, 1 nonsense_mediated_decay, 1 retained_intron, 1 protein_coding_CDS_not_defined

ENST00000272249, ENST00000358367, ENST00000378915, ENST00000409328, ENST00000409636, ENST00000410076, ENST00000425682, ENST00000441689, ENST00000449105, ENST00000488099, ENST00000498516, ENST00000608859

RefSeq mRNA: 2 — MANE Select: NM_138394 NM_001142650, NM_138394

CCDS: CCDS1796, CCDS46261

Canonical transcript exons

ENST00000449105 — 13 exons

Exon	Start	End
ENSE00000962485	38591530	38591648
ENSE00001210568	38581913	38581985
ENSE00001210572	38585644	38585881
ENSE00001586313	38582072	38582168
ENSE00001860993	38602438	38602928
ENSE00003495126	38568386	38568443
ENSE00003550637	38569133	38569334
ENSE00003553028	38568199	38568297
ENSE00003589430	38577461	38577532
ENSE00003648708	38573210	38573427
ENSE00003682755	38569804	38569925
ENSE00003687211	38583841	38583926
ENSE00003844262	38561969	38564237

Expression profiles

Bgee: expression breadth ubiquitous, 259 present calls, max score 96.77.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 23.5046 / max 1041.2367, expressed in 1814 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
27881	11.8332	1787
27880	6.5227	1670
27883	2.1880	675
27882	1.1715	767
27879	0.9724	581
27878	0.4161	198
27877	0.2792	105
27884	0.1216	41

Top tissues by expression

260 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	96.77	gold quality
embryo	UBERON:0000922	96.64	gold quality
ganglionic eminence	UBERON:0004023	96.64	gold quality
adrenal tissue	UBERON:0018303	94.73	gold quality
adult organism	UBERON:0007023	94.66	gold quality
epithelial cell of pancreas	CL:0000083	94.54	gold quality
cartilage tissue	UBERON:0002418	93.68	gold quality
cortical plate	UBERON:0005343	93.56	gold quality
parotid gland	UBERON:0001831	93.12	gold quality
cauda epididymis	UBERON:0004360	92.79	gold quality
left testis	UBERON:0004533	92.74	gold quality
right testis	UBERON:0004534	92.58	gold quality
saphenous vein	UBERON:0007318	92.43	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.29	gold quality
bone marrow	UBERON:0002371	92.19	gold quality
smooth muscle tissue	UBERON:0001135	92.09	gold quality
testis	UBERON:0000473	91.98	gold quality
right uterine tube	UBERON:0001302	91.95	gold quality
endothelial cell	CL:0000115	91.94	gold quality
popliteal artery	UBERON:0002250	91.78	gold quality
tibial artery	UBERON:0007610	91.77	gold quality
lower esophagus muscularis layer	UBERON:0035833	91.60	gold quality
lower esophagus	UBERON:0013473	91.56	gold quality
body of uterus	UBERON:0009853	91.54	gold quality
artery	UBERON:0001637	91.50	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	91.44	gold quality
mucosa of stomach	UBERON:0001199	91.43	gold quality
bronchial epithelial cell	CL:0002328	91.38	gold quality
right lung	UBERON:0002167	91.31	gold quality
aorta	UBERON:0000947	91.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

71 targeting HNRNPLL, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-5692A	100.00	74.40	6850
HSA-MIR-3163	100.00	77.23	8605
HSA-MIR-3134	100.00	66.43	777
HSA-MIR-3646	100.00	73.56	5283
HSA-MIR-4795-3P	100.00	74.62	4024
HSA-MIR-3662	99.99	73.82	5684
HSA-MIR-4282	99.99	75.36	6408
HSA-MIR-4803	99.98	71.99	3117
HSA-MIR-3065-5P	99.97	71.56	3281
HSA-MIR-570-3P	99.96	72.41	4910
HSA-MIR-1468-3P	99.96	72.74	3797
HSA-MIR-4666A-3P	99.96	71.71	3434
HSA-MIR-3658	99.96	73.87	4379
HSA-MIR-381-3P	99.93	71.87	2854
HSA-MIR-300	99.92	71.76	2856
HSA-MIR-10523-5P	99.91	69.22	2038
HSA-MIR-3529-3P	99.90	73.55	3045
HSA-MIR-4307	99.82	70.45	3374
HSA-MIR-4760-5P	99.80	69.88	1619
HSA-MIR-4517	99.76	69.19	1867
HSA-MIR-6505-5P	99.73	69.25	1595
HSA-MIR-5580-3P	99.70	69.41	2052
HSA-MIR-3618	99.69	68.57	1012
HSA-MIR-379-3P	99.69	69.60	1524
HSA-MIR-411-3P	99.69	69.63	1524
HSA-MIR-10393-5P	99.65	68.01	1368
HSA-MIR-8061	99.63	69.44	1411
HSA-MIR-3942-3P	99.57	69.03	2854
HSA-MIR-4708-3P	99.51	67.99	870
HSA-MIR-513C-5P	99.50	68.42	1730

Literature-anchored findings (GeneRIF, showing 7)

• Participation of SRRF (Stromal RNA Regulating Factor) isoforms in post-transcriptional events in bone marrow stromal cells; an important role in regulation of the RNA expression that directs the bone marrow stromal cells differentiation pathway (PMID:15256261)
• identification of heterogeneous ribonucleoprotein L-like (hnRNPLL) as a critical inducible regulator of CD45 alternative splicing (PMID:18669861)
• These data establish that hnRNP LL plays a critical and unique role in the signal-induced regulation of CD45 and demonstrate the utility of cell-based screens for the identification of novel splicing regulatory factors. (PMID:18719244)
• Loss-of-function mutation of hnRNPLL disrupts peripheral T cell accumulation even in the absence of CD45 protein, indicating that hnRNPLL acts through an independent mechanism to promote peripheral T cell longevity. (PMID:20505149)
• The findings demonstrate that the hnRNP L and LL proteins differentially control gene expression programs at multiple levels in the production of two physiologically important hormones. (PMID:29610151)
• intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation (PMID:29769310)
• MYB mediates downregulation of the colorectal cancer metastasis suppressor heterogeneous nuclear ribonucleoprotein L-like during epithelial-mesenchymal transition. (PMID:34286904)

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000116101
mus_musculus	Hnrnpll	ENSMUSG00000024095
rattus_norvegicus	Hnrnpll	ENSRNOG00000006929
drosophila_melanogaster	sm	FBGN0003435
caenorhabditis_elegans		WBGENE00016624

Paralogs (5): PTBP1 (ENSG00000011304), HNRNPL (ENSG00000104824), PTBP2 (ENSG00000117569), PTBP3 (ENSG00000119314), RBM20 (ENSG00000203867)

Protein

Protein identifiers

Heterogeneous nuclear ribonucleoprotein L-like — Q8WVV9 (reviewed: Q8WVV9)

Alternative names: Stromal RNA-regulating factor

All UniProt accessions (8): Q8WVV9, A0A0S2Z6K1, B7WPG3, C9IYN3, C9JJZ7, H7BXH8, H7C464, V9GYK2

UniProt curated annotations — full annotation on UniProt →

Function. RNA-binding protein that functions as a regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.

Subunit / interactions. Interacts with HNRNPL.

Tissue specificity. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.

Induction. Up-regulated in stimulated T-cells.

Isoforms (5)

UniProt ID	Names	Canonical?
Q8WVV9-1	1	yes
Q8WVV9-2	2
Q8WVV9-3	3
Q8WVV9-4	4
Q8WVV9-5	5

RefSeq proteins (2): NP_001136122, NP_612403* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR000504	RRM_dom	Domain
IPR006536	HnRNP-L/PTB	Family
IPR012677	Nucleotide-bd_a/b_plait_sf	Homologous_superfamily
IPR021790	PTBP1-like_RRM2	Domain
IPR034983	hnRPLL_RRM3	Domain
IPR034985	hnRPLL_RRM1	Domain
IPR034986	hnRPLL_RRM2	Domain
IPR034987	hnRPLL_RRM4	Domain
IPR035979	RBD_domain_sf	Homologous_superfamily
IPR055204	HNRNPL_RRM	Domain

Pfam: PF00076, PF11835, PF13893, PF22976

UniProt features (28 total): splice variant 6, modified residue 5, strand 5, domain 3, cross-link 2, helix 2, compositionally biased region 2, chain 1, turn 1, region of interest 1

Structure

Experimental structures (PDB)

1 structures.

PDB	Method	Resolution (Å)
7EVS	X-RAY DIFFRACTION	1.6

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8WVV9-F1	76.11	0.49

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (7): 68, 75, 26, 491, 35, 46, 59

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 217 (showing top): GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN, CCAWYNNGAAR_UNKNOWN, GOBP_POSITIVE_REGULATION_OF_RNA_SPLICING, IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR, BOYLAN_MULTIPLE_MYELOMA_D_DN, MODULE_331, YU_MYC_TARGETS_UP, MARTINEZ_RB1_TARGETS_DN, SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP, GOBP_RNA_SPLICING, OCT1_06, MARSON_FOXP3_TARGETS_UP, DODD_NASOPHARYNGEAL_CARCINOMA_UP, NRF2_01, ZHANG_BREAST_CANCER_PROGENITORS_UP

GO Biological Process (3): mRNA processing (GO:0006397), positive regulation of RNA splicing (GO:0033120), regulation of RNA splicing (GO:0043484)

GO Molecular Function (4): RNA binding (GO:0003723), mRNA binding (GO:0003729), nucleic acid binding (GO:0003676), protein binding (GO:0005515)

GO Cellular Component (4): nucleus (GO:0005634), membrane (GO:0016020), synapse (GO:0045202), ribonucleoprotein complex (GO:1990904)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
RNA splicing	2
binding	2
RNA processing	1
mRNA metabolic process	1
positive regulation of gene expression	1
regulation of RNA splicing	1
regulation of gene expression	1
regulation of primary metabolic process	1
nucleic acid binding	1
RNA binding	1
intracellular membrane-bounded organelle	1
cellular anatomical structure	1
cell junction	1
protein-containing complex	1

Protein interactions and networks

STRING

994 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
HNRNPLL	PTPRC	P08575	799
HNRNPLL	HNRNPH1	P31943	612
HNRNPLL	PCBP2	Q15366	610
HNRNPLL	TP53	P04637	582
HNRNPLL	HNRNPC	P07910	565
HNRNPLL	SRSF3	P23152	564
HNRNPLL	HNRNPU	Q00839	561
HNRNPLL	SRSF5	Q13243	560
HNRNPLL	SRSF4	Q08170	553
HNRNPLL	SRSF6	Q13247	547
HNRNPLL	U2AF2	P26368	546
HNRNPLL	SRSF7	Q16629	545
HNRNPLL	SRSF2	Q01130	531
HNRNPLL	HNRNPDL	O14979	523
HNRNPLL	RRM2	P31350	507

IntAct

120 interactions, top by confidence:

A	B	Type	Score
HNRNPLL	HNRNPK	psi-mi:“MI:0915”(physical association)	0.720
HNRNPK	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.720
HNRNPLL	HNRNPK	psi-mi:“MI:0915”(physical association)	0.670
HNRNPK	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.670
BOLL	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.670
QKI	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.670
MDFI	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.670
HNRNPLL	BOLL	psi-mi:“MI:0915”(physical association)	0.670
HNRNPLL	QKI	psi-mi:“MI:0915”(physical association)	0.670
HNRNPLL	MDFI	psi-mi:“MI:0915”(physical association)	0.670
DAB1	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.560
UBE2I	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.560
RBPMS	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.560
RHOXF2	HNRNPLL	psi-mi:“MI:0915”(physical association)	0.560
HNRNPLL	THAP1	psi-mi:“MI:0915”(physical association)	0.560
HNRNPLL	DAB1	psi-mi:“MI:0915”(physical association)	0.560

BioGRID (229): HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Two-hybrid), HNRNPLL (Affinity Capture-MS), HNRNPLL (Affinity Capture-MS), HNRNPLL (Affinity Capture-MS), HNRNPLL (Affinity Capture-MS), CCNB2 (Co-fractionation)

ESM2 similar proteins: A1L1G1, A7MBL8, A8KBF6, B2RYD2, O00560, O08874, O08992, O60733, O94806, P10687, P10894, P29074, P70175, P97570, Q16513, Q28C55, Q3SYX0, Q3US41, Q4R4Q3, Q5PYH7, Q5R8R4, Q5ZLR4, Q62433, Q62936, Q640Z1, Q69YN2, Q6DCD0, Q6DEZ7, Q6DFS4, Q6DIX1, Q6GQL1, Q6JE36, Q6NXG1, Q6P0D7, Q6R005, Q7ZVR8, Q7ZY29, Q8BPM2, Q8BWW9, Q8K0G8

Diamond homologs: F1LQ48, P14866, Q8R081, Q8WVV9, Q921F4, Q9FGL9, Q9MAC5, O95758, P17225, P26599, Q00438, Q29099, Q66H20, Q6ICX4, Q8BHD7, Q8WN55, Q91Z31, Q9UKA9, Q9Z118, E9PT37, P0DW16, P25299, Q3UQS8, Q5T481

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 109 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

Reactome pathways:

Pathway	Partners	Fold	FDR
mRNA Polyadenylation	7	9.2×	5e-03
Processing of Capped Intron-Containing Pre-mRNA	7	8.6×	5e-03
mRNA Splicing - Major Pathway	8	6.5×	6e-03

Disease & clinical

Clinical variants and AI predictions

ClinVar

60 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	47
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

2511 predictions. Top by Δscore:

Variant	Effect	Δscore
2:38568193:A:AC	donor_gain	1.0000
2:38568194:C:CC	donor_gain	1.0000
2:38568194:CTTA:C	donor_gain	1.0000
2:38568195:TTAC:T	donor_loss	1.0000
2:38568196:TACTC:T	donor_loss	1.0000
2:38568197:A:AC	donor_gain	1.0000
2:38568197:A:C	donor_loss	1.0000
2:38568197:ACT:A	donor_gain	1.0000
2:38568198:C:CA	donor_gain	1.0000
2:38568198:CT:C	donor_gain	1.0000
2:38568198:CTC:C	donor_gain	1.0000
2:38568198:CTCG:C	donor_gain	1.0000
2:38568198:CTCGG:C	donor_gain	1.0000
2:38568211:T:C	donor_gain	1.0000
2:38568293:TGAAG:T	acceptor_gain	1.0000
2:38568294:GAAG:G	acceptor_gain	1.0000
2:38568295:AAG:A	acceptor_gain	1.0000
2:38568296:AG:A	acceptor_gain	1.0000
2:38568298:C:CC	acceptor_gain	1.0000
2:38568304:C:CT	acceptor_gain	1.0000
2:38568305:A:T	acceptor_gain	1.0000
2:38568379:CACTT:C	donor_loss	1.0000
2:38568380:ACTT:A	donor_loss	1.0000
2:38568381:CT:C	donor_loss	1.0000
2:38568382:TTAC:T	donor_loss	1.0000
2:38568383:TACG:T	donor_loss	1.0000
2:38568384:A:AC	donor_gain	1.0000
2:38568384:ACGTT:A	donor_loss	1.0000
2:38568385:C:A	donor_loss	1.0000
2:38568385:C:CC	donor_gain	1.0000

AlphaMissense

3534 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
2:38564201:G:A	S537F	1.000
2:38564203:A:C	F536L	1.000
2:38564203:A:T	F536L	1.000
2:38564204:A:G	F536S	1.000
2:38564205:A:G	F536L	1.000
2:38564206:G:C	C535W	1.000
2:38564207:C:T	C535Y	1.000
2:38564208:A:G	C535R	1.000
2:38564210:A:G	L534P	1.000
2:38564210:A:T	L534H	1.000
2:38564212:C:A	K533N	1.000
2:38564212:C:G	K533N	1.000
2:38564214:T:C	K533E	1.000
2:38568219:T:G	H518P	1.000
2:38568221:A:C	N517K	1.000
2:38568221:A:T	N517K	1.000
2:38568225:A:G	L516P	1.000
2:38568234:A:G	L513P	1.000
2:38568234:A:T	L513H	1.000
2:38568246:G:T	A509E	1.000
2:38568265:A:G	W503R	1.000
2:38568265:A:T	W503R	1.000
2:38568273:A:G	L500P	1.000
2:38568276:C:A	G499V	1.000
2:38568276:C:T	G499E	1.000
2:38568277:C:A	G499W	1.000
2:38568277:C:G	G499R	1.000
2:38568277:C:T	G499R	1.000
2:38568396:A:C	F488L	1.000
2:38568396:A:T	F488L	1.000

dbSNP variants (sampled 300 via entrez): RS1000005261 (2:38561575 A>C,T), RS1000120394 (2:38564020 G>A,C,T), RS1000137908 (2:38597754 T>A), RS1000246726 (2:38566942 G>C), RS1000295617 (2:38579448 T>A), RS1000361751 (2:38589037 A>G), RS1000426814 (2:38597473 G>A,C), RS1000440656 (2:38572874 C>T), RS1000471628 (2:38573073 T>C), RS1000528602 (2:38583316 A>G), RS1000602270 (2:38577951 C>G,T), RS1000615800 (2:38578692 C>G), RS1000668811 (2:38579166 G>A), RS1000720691 (2:38593483 G>A), RS1000808322 (2:38571694 T>A)

Disease associations

OMIM: gene MIM:611208 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

1 associations (top):

Study	Trait	p-value
GCST004904_222	Body mass index	9.000000e-09

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0004340	body mass index

Drugs & pharmacology

Drug and pharmacology data

Is drug target: yes

ChEMBL targets (1): CHEMBL5724650 (SINGLE PROTEIN)

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

38 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Valproic Acid	affects expression, decreases expression, decreases methylation	4
trichostatin A	affects cotreatment, decreases expression	3
sodium arsenite	decreases expression, increases expression	2
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	affects cotreatment, increases expression, decreases expression	2
FR900359	affects phosphorylation	1
urushiol	increases expression	1
ethylbenzene	increases expression	1
beta-lapachone	decreases expression	1
perfluorooctanoic acid	increases expression	1
2-xylene	increases expression	1
coumarin	affects phosphorylation	1
di-n-butylphosphoric acid	affects expression	1
perfluorooctane sulfonic acid	increases expression	1
dorsomorphin	affects cotreatment, decreases expression	1
bisphenol S	increases methylation	1
jinfukang	decreases expression	1
LDN 193189	affects cotreatment, increases expression	1
(+)-JQ1 compound	increases expression	1
Bortezomib	increases expression	1
Benzene	increases expression	1
Cadmium	increases abundance, increases expression	1
Caffeine	decreases phosphorylation	1
Endosulfan	decreases expression	1
Enzyme Inhibitors	increases O-linked glycosylation, decreases activity	1
Ivermectin	decreases expression	1
Methylene Chloride	increases expression	1
Oxazolone	increases expression	1
Phthalic Acids	increases methylation	1
Quercetin	decreases phosphorylation	1
Ribonucleotides	affects binding	1

ChEMBL screening assays

7 unique, capped per target: 7 binding

Representative assays (with source publication via chembl_document):

Assay ID	Type	Description	Source paper
CHEMBL5651577	Binding	Binding affinity to human HNRNPLL incubated for 45 mins by Kinobead based pull down assay	NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. — ChemMedChem

Cellosaurus cell lines

1 cell lines: 1 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_E0EC	Ubigene HeLa HNRNPLL KO	Cancer cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.