HOMER3-AS1

Summary

HOMER3-AS1 (HOMER3 antisense RNA 1, HGNC:53775) is a long non-coding RNA gene on chromosome 19p13.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53775
Approved symbol	HOMER3-AS1
Name	HOMER3 antisense RNA 1
Location	19p13.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269019
Ensembl biotype	lncRNA
Entrez	102724360
RNAcentral	URS0000A77656 — lncRNA, 1045 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000601106, ENST00000775353, ENST00000775354

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000601106 — 3 exons

Exon	Start	End
ENSE00003183340	18946081	18946228
ENSE00004142098	18940235	18940624
ENSE00004142102	18946326	18947492

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 79.97.

FANTOM5 (CAGE): breadth broad, TPM avg 1.8419 / max 70.6597, expressed in 837 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
174749	1.6395	763
174750	0.2024	76

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.97	silver quality
sural nerve	UBERON:0015488	70.31	gold quality
muscle of leg	UBERON:0001383	65.38	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.37	gold quality
gastrocnemius	UBERON:0001388	65.05	gold quality
skeletal muscle tissue	UBERON:0001134	64.31	gold quality
monocyte	CL:0000576	61.72	gold quality
stromal cell of endometrium	CL:0002255	61.53	gold quality
leukocyte	CL:0000738	61.49	gold quality
bone marrow	UBERON:0002371	58.58	gold quality
ganglionic eminence	UBERON:0004023	57.93	gold quality
ventricular zone	UBERON:0003053	57.64	silver quality
blood	UBERON:0000178	57.29	gold quality
granulocyte	CL:0000094	55.86	gold quality
spleen	UBERON:0002106	55.38	gold quality
lymph node	UBERON:0000029	54.68	gold quality
right coronary artery	UBERON:0001625	53.94	gold quality
placenta	UBERON:0001987	53.86	gold quality
metanephros cortex	UBERON:0010533	53.83	gold quality
cortex of kidney	UBERON:0001225	52.60	gold quality
prefrontal cortex	UBERON:0000451	52.58	gold quality
gall bladder	UBERON:0002110	52.55	gold quality
endocervix	UBERON:0000458	51.55	gold quality
liver	UBERON:0002107	50.92	gold quality
kidney	UBERON:0002113	50.72	gold quality
thoracic aorta	UBERON:0001515	50.37	gold quality
descending thoracic aorta	UBERON:0002345	50.31	gold quality
left adrenal gland cortex	UBERON:0035825	50.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	50.13	gold quality
ascending aorta	UBERON:0001496	50.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.