HOXB-AS2

Summary

HOXB-AS2 (HOXB cluster antisense RNA 2, HGNC:40284) is a long non-coding RNA gene on chromosome 17q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40284
Approved symbol	HOXB-AS2
Name	HOXB cluster antisense RNA 2
Location	17q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239552
Ensembl biotype	lncRNA
Entrez	100874350
RNAcentral	URS00021231B1 — lncRNA, 3594 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000464382

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000464382 — 2 exons

Exon	Start	End
ENSE00001853412	48557262	48557358
ENSE00001894771	48559586	48560333

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 84.23.

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	84.23	gold quality
sural nerve	UBERON:0015488	82.96	gold quality
mucosa of stomach	UBERON:0001199	74.06	gold quality
metanephros cortex	UBERON:0010533	73.60	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.49	gold quality
lower esophagus	UBERON:0013473	72.46	gold quality
colonic epithelium	UBERON:0000397	72.26	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	72.07	gold quality
fallopian tube	UBERON:0003889	72.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.80	gold quality
esophagus	UBERON:0001043	68.56	gold quality
endometrium	UBERON:0001295	68.45	gold quality
colon	UBERON:0001155	68.20	gold quality
cortex of kidney	UBERON:0001225	67.23	gold quality
intestine	UBERON:0000160	67.07	gold quality
transverse colon	UBERON:0001157	66.92	gold quality
kidney	UBERON:0002113	65.59	gold quality
small intestine Peyer’s patch	UBERON:0003454	65.22	gold quality
small intestine	UBERON:0002108	64.92	gold quality
esophagus mucosa	UBERON:0002469	64.79	gold quality
vagina	UBERON:0000996	64.23	gold quality
rectum	UBERON:0001052	64.19	gold quality
right lung	UBERON:0002167	64.11	gold quality
omental fat pad	UBERON:0010414	63.03	gold quality
adult mammalian kidney	UBERON:0000082	62.93	gold quality
left uterine tube	UBERON:0001303	62.58	gold quality
descending thoracic aorta	UBERON:0002345	61.89	gold quality
thoracic mammary gland	UBERON:0005200	61.67	gold quality
lower esophagus mucosa	UBERON:0035834	61.57	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Genome-wide screening of functional long noncoding RNAs in the epicardial adipose tissues of atrial fibrillation. (PMID:32147422)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.