HOXB-AS4

Summary

HOXB-AS4 (HOXB cluster antisense RNA 4, HGNC:40285) is a long non-coding RNA gene on chromosome 17q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40285
Approved symbol	HOXB-AS4
Name	HOXB cluster antisense RNA 4
Location	17q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242207
Ensembl biotype	lncRNA
Entrez	100874351
RNAcentral	URS0002123147 — lncRNA, 543 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000462131, ENST00000480386

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462131 — 2 exons

Exon	Start	End
ENSE00001916825	48634551	48634661
ENSE00001931596	48629549	48629651

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 91.44.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
rectum	UBERON:0001052	91.44	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.69	gold quality
mucosa of transverse colon	UBERON:0004991	88.52	gold quality
transverse colon	UBERON:0001157	86.69	gold quality
colon	UBERON:0001155	78.08	gold quality
intestine	UBERON:0000160	77.63	gold quality
small intestine Peyer’s patch	UBERON:0003454	76.55	gold quality
colonic epithelium	UBERON:0000397	76.44	gold quality
small intestine	UBERON:0002108	76.20	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.43	gold quality
vermiform appendix	UBERON:0001154	66.63	gold quality
metanephros cortex	UBERON:0010533	64.99	gold quality
multicellular organism	UBERON:0000468	60.01	gold quality
muscle layer of sigmoid colon	UBERON:0035805	59.94	gold quality
islet of Langerhans	UBERON:0000006	59.85	gold quality
monocyte	CL:0000576	59.84	gold quality
right testis	UBERON:0004534	59.65	gold quality
right frontal lobe	UBERON:0002810	58.39	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.25	gold quality
liver	UBERON:0002107	57.96	gold quality
right adrenal gland	UBERON:0001233	57.91	gold quality
cortex of kidney	UBERON:0001225	57.71	gold quality
left testis	UBERON:0004533	57.22	gold quality
testis	UBERON:0000473	56.97	gold quality
kidney	UBERON:0002113	56.79	gold quality
ovary	UBERON:0000992	56.75	gold quality
granulocyte	CL:0000094	56.47	gold quality
adult mammalian kidney	UBERON:0000082	56.23	gold quality
right atrium auricular region	UBERON:0006631	55.81	gold quality
placenta	UBERON:0001987	55.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.