HPGD-AS2

Summary

HPGD-AS2 (HPGD antisense RNA 2, HGNC:58913) is a long non-coding RNA gene on chromosome 4q34.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58913
Approved symbol	HPGD-AS2
Name	HPGD antisense RNA 2
Location	4q34.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251584
Ensembl biotype	lncRNA
Entrez	105377548

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000507483, ENST00000664316, ENST00000752451, ENST00000752452, ENST00000752453, ENST00000752454, ENST00000752455, ENST00000752456, ENST00000752457, ENST00000752458, ENST00000752459, ENST00000752460, ENST00000752461, ENST00000752462, ENST00000752463, ENST00000752464

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507483 — 3 exons

Exon	Start	End
ENSE00002028177	174538132	174538212
ENSE00002056913	174536640	174536881
ENSE00002071217	174540316	174540784

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 87.49.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.49	gold quality
right lung	UBERON:0002167	71.29	gold quality
duodenum	UBERON:0002114	70.62	gold quality
mucosa of transverse colon	UBERON:0004991	69.08	gold quality
placenta	UBERON:0001987	67.76	gold quality
rectum	UBERON:0001052	67.54	gold quality
small intestine	UBERON:0002108	66.83	gold quality
small intestine Peyer’s patch	UBERON:0003454	66.62	gold quality
transverse colon	UBERON:0001157	65.29	gold quality
lower esophagus mucosa	UBERON:0035834	65.05	gold quality
intestine	UBERON:0000160	64.17	gold quality
colon	UBERON:0001155	63.28	gold quality
muscle tissue	UBERON:0002385	61.52	gold quality
blood	UBERON:0000178	61.51	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.15	gold quality
smooth muscle tissue	UBERON:0001135	60.00	gold quality
liver	UBERON:0002107	59.76	gold quality
right lobe of liver	UBERON:0001114	59.38	gold quality
skin of leg	UBERON:0001511	59.31	gold quality
myometrium	UBERON:0001296	59.06	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.69	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	58.44	gold quality
lung	UBERON:0002048	58.31	gold quality
upper lobe of left lung	UBERON:0008952	57.87	gold quality
body of uterus	UBERON:0009853	57.82	gold quality
zone of skin	UBERON:0000014	57.23	gold quality
lower esophagus	UBERON:0013473	57.05	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.05	gold quality
vagina	UBERON:0000996	56.65	gold quality
body of stomach	UBERON:0001161	56.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.